JDRF Artificial Pancreas Project Consortium


ProtocolStatusStart DateEnd DateClinical Trial IDDetailsPublic Dataset
Comparison of standard continuous subcutaneous insulin infusion and closed-loop delivery (APCam01)Closed03/07/2007 08/06/2007 NAView  
Comparison of closed-loop delivery after large (130g CHO) rapidly and slowly absorbed meals (APCam02)Closed08/06/2007 12/20/2007 NAView  
Comparison of standard continuous subcutaneous insulin infusion and closed-loop delivery after afternoon exercise (APCam03)Closed12/20/2007 05/28/2008 NAView  
Closed-loop Glucose Control for Automated Management of Type 1 DiabetesClosed05/01/2008 10/01/2009 NCT00811317View  
Study of Closed-Loop Glucose Control in People with Type 1 Diabetes (BPK004)Closed05/22/2008 02/01/2009 NCT00977808View  
Controlled Insulin Delivery: Combining Technology With TreatmentClosed07/01/2008 01/01/2010 NCT01484457View  
Validation of the Gut Absorption Rate of Glucose During a Large, Slowly and Rapidly-absorbed Evening Meal in Subjects With Type 1 Diabetes (APCam04)Closed11/01/2008 06/01/2011 NCT02782195View  
A Comparison of Two Sensor-Augmented Glycemic Control Systems in Persons With Type 1 Diabetes Mellitus: Subcutaneous (SC) Insulin and Glucagon Delivery vs. SC Insulin OnlyClosed11/01/2008 09/01/2009 NCT00797823View  
Automated Overnight Closed-loop Glucose Control in Young People With Type 1 Diabetes (APCam05)Closed02/01/2009 12/01/2011 NCT00989898View  
Closing the Loop in Adults With Type 1 Diabetes (ANGELA01)Closed02/01/2009 07/02/2009 NCT00910767View  
Feasibility Study of a Modular Control to Range System in T1DM (MDB004)Closed10/01/2009 12/01/2010 NCT01418703View  
Closing the Loop for 36 Hours in Adolescents With Type 1 Diabetes (Dan01)Closed03/01/2010 10/01/2010 NCT01074801View  
Integration of Continuous Glucose Monitoring Into a Bi-Hormonal Closed-Loop Artificial Pancreas for Automated Management of Type 1 DiabetesClosed07/01/2010 06/01/2013 NCT01161862View  
Use of the Adaptive Proportional Derivative Insulin and Glucagon Delivery System to Control Blood Glucose in People with Type 1 Diabetes Treated with HydrocortisoneClosed10/06/2010 05/01/2011 NAView  
A Study to Evaluate a Multiple Model Probabilistic Predictive Controller for Closed Loop Insulin Delivery (MMPPC)Closed02/01/2011 11/01/2013 NCT01492062View  
Pilot Study using Fuzzy Logic Controller for an Artificial PancreasClosed02/25/2011 12/31/2011 NAView  
Inpatient Evaluation of an Automated Closed-Loop Control-to-Range System (CTR)Closed03/21/2011 09/01/2012 NCT01271023View  
Closing the Loop for 36 Hours in Adolescents With Type 1 Diabetes: Evaluation of Reduced Meal Bolusing (Dan02)Closed04/01/2011 09/01/2011 NCT01629251View  
Effect of Pramlintide on Prandial Glycemic Excursions During Closed-Loop Control in Adolescents and Young Adults With Type 1 DiabetesClosed04/13/2011 03/15/2013 NAView  
Closing the Loop in Adolescents During Non-compliance BehavioursClosed07/01/2011 05/01/2012 NCT01629277View  
Feasibility Assessment of Prototype Nocturnal Hypoglycemia Reduction System for Outpatient StudyClosed08/05/2011 07/15/2012 NAView  
Feasibility Study of a Portable Artificial Pancreas System in Type 1 Diabetes - FranceClosed09/01/2011 11/01/2012 NCT01447979View  
Feasibility Study of a Portable Artificial Pancreas System in Type 1 Diabetes - ItalyClosed09/01/2011 06/01/2014 NCT01447992View  
Medtronic Treat to Range Closed-Loop Control: Tuning a Treat-to-Range Controller for the Effects of High and Low Glycemic Index Meals (TTR)Closed11/01/2011 12/01/2013 NCT01490151View  
Feasibility Study Using Zone-MPC Controller (Zone-Model Predictive Control) and Health Monitoring System (HMS)Closed11/01/2011 03/01/2014 NCT01472406View  
Prevention of Nocturnal Hypoglycemia using predictive algorithms and pump shut-off.Closed01/01/2012 06/01/2012 NCT01736930View  Download
Closed Loop Artificial Pancreas Using Intraperitoneal (IP) Insulin Via DiaPort®Closed02/01/2012 03/01/2013 NCT01555788View  
Sensor-controlled Insulin- and Glucagon Delivery in Subjects With Type 1 Diabetes: Testing of an Automated System in a Supervised Inpatient SettingClosed03/01/2012 09/01/2013 NCT01552603View  
Outpatient Control-to-Range: System and Monitoring TestingClosed04/01/2012 06/01/2012 NCT01578980View  
Closing the Loop in Youth With Type 1 Diabetes in the Home Setting (APCam06)Closed06/01/2012 03/21/2013 NCT01221467View  
Early Feasibility Study 2 of Outpatient Control-to-Range - Testing System EfficacyClosed10/01/2012 01/01/2013 NCT01714505View  
Feasibility Study Using Zone-MPC Controller (Zone-Model Predictive Control) and Health Monitoring System (HMS) and Technosphere® Insulin Inhalation System From MannnKind Corp.Closed10/01/2012 06/01/2013 NCT01874392View  
Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension: An Outpatient Pilot Feasibility and Efficacy Study (PSO3)Closed11/01/2012 07/01/2013 NCT01591681View  Download
Artificial Pancreas using a Fuzzy Logic Controller During Exercise and High Carbohydrate-High Fat MealClosed11/01/2012 06/01/2013 NAView  
Closing the Loop in Young Children With Type 1 Diabetes (APCam10)Closed12/01/2012 12/01/2013 NCT01557634View  
Effect of the Insupatch on Automated Closed-loop Glucose Control in Type 1 DiabetesClosed01/01/2013 12/01/2015 NCT01787318View  
Early Feasibility Study 2 of Outpatient Control-to-Range - Testing System Efficacy (Italy)Closed01/01/2013 05/01/2013 NCT01727817View  
Sensor-controlled Insulin- and Glucagon Delivery in Subjects With Type 1 Diabetes: Testing of an Automated System in an Outpatient (Hotel) Setting.Closed05/01/2013 10/01/2013 NCT01871870View  
Outpatient Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension in Children (PSO4)Closed05/01/2013 09/01/2014 NCT01823341View  Download
Early Feasibility Study 2 of Outpatient Control-to-Range - Testing System Efficacy (France)Closed05/01/2013 05/31/2013 NCT01742741View  
Closed-loop Control of Glucose Levels After Meal Intake in Adults With Type 1 DiabetesClosed08/01/2013 02/01/2014 NCT01930097View  
Crossover Feasibility Study of Portable AP Device With Zone-MPC and HMS and Adapted I:C and Basal Insulin (DP3)Closed11/01/2013 11/01/2014 NCT01929798View  
Closing the Loop in Children and Adolescents With Type 1 Diabetes in the Home Setting (APCam08)Closed12/01/2013 05/01/2015 NCT01778348View  
The Performance of an Artificial Pancreas at Home in People With Type 1 DiabetesClosed01/01/2014 12/01/2015 NCT02040571View  
Automated Closed-loop in Children and Adolescents With Type 1 Diabetes (APCam09)Closed04/01/2014 04/01/2015 NCT02129868View  
Closing the Loop 24/7 in Adolescents With Type 1 Diabetes (DAN04)Closed07/01/2014 12/01/2016 NCT01873066View  
Feasibility Study of Using a PID (Proportional-Integral-Derivative) Controller Versus an MPC (Model Predictive Control) Controller Algorithm and Health Monitoring System (HMS)Closed07/01/2014 01/01/2015 NCT01987206View  
Pilot Study 3 of Outpatient Control-to-Range: Safety and Efficacy With Day-and-Night In-Home Use (CTR3)Closed08/01/2014 11/01/2015 NCT02137512View  
Early Feasibility Study of a Zone-Model Predictive Control (MPC) Controller and a Health Monitoring System (HMS) With the Diabetes Assistant (DiAS) in the Outpatient SettingRecruiting05/01/2015 10/01/2015 NCT02463682View  
Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms (PHM2)Closed06/01/2015 06/01/2016 NCT02438189View  
Feasibility Study to Evaluate the Hybrid-Logic Closed Loop System in Type 1 DiabetesClosed12/01/2015 04/01/2016 NCT02692547View  
Project Nightlight: Efficacy and System Acceptance of Dinner/Night vs. 24hr Closed Loop ControlRecruiting02/01/2016 10/01/2018 NCT02679287View  
At Home Study of a Zone-Model Predictive Control (MPC) Controller and a Health Monitoring System (HMS) With the Diabetes Assistant (DiAs) System and Run-to-Run AdaptationRecruiting02/01/2016 12/01/2016 NCT02705053View  
Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms, Pump Suspension, and Insulin Dosing in Children and Young Adolescents (PHM3)Recruiting04/01/2016 10/01/2016 NCT02714972View  
A Randomized Crossover Study to Evaluate the Efficacy of Fault Detection Algorithms Using the ZoneMPC Algorithm and DiAs System in Adult Subjects With Type 1 Diabetes in the Outpatient SettingUpcoming05/01/2016 12/01/2016 NCT02773875View  
Home Testing of Day and Night Closed Loop With Pump Suspend Feature (APCam11)Recruiting05/01/2016 10/01/2017 NCT02523131View  
Feasibility Study to Evaluate the Hybrid-Logic Closed Loop System in Type 1 Diabetes -Single-arm, Single-center, in Clinic Study-The DREAMED TrailRecruiting06/01/2016 09/01/2016 NCT02651181View  
Effect of Basal-Bolus Closed-Loop Co-Administration of Insulin and Pramlintide on Improving the Glycemic Control in Type 1 DiabetesUpcoming09/01/2016 12/01/2017 NCT02814123View  
Closed-loop Control of Postprandial Glucose Levels in Children and Adults With Type 1 DiabetesUpcoming12/01/2016 06/01/2017 NCT02490098View  



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