JDRF Artificial Pancreas Project Consortium
  
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Manuscripts

General

1. Chassin LJ, Wilinska ME, Hovorka R. Intense Exercise in Type 1 Diabetes: Exploring the Role of Continuous Glucose Monitoring. J Diabetes Sci Technol 1:570-583, 2007 (Published).
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2. Gillis R, Palerm CC, Zisser H, Jovanovic L, Seborg DE, Doyle FJ. Glucose Estimation and Prediction Through Meal Responses Using Ambulatory Subject Data for Advisory Mode Model Predictive Control. J Diabetes Sci Technol 1:825-833, 2007 (Published).
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3. Hovorka R and Dunger DB. Closed-loop Insulin Delivery Systems. European Paediatrics Review 1:54-56, 2007 (Published).
(Manuscript)  
 
4. Hovorka R, Wilinska ME, Chassin LJ, Acerini CL, Dunger DB. The Artificial Pancreas: Making Headway. Pract Diabetes Int 24:56-58, 2007 (Published).
(Manuscript)  
 
5. Palerm CC, Zisser H, Jovanovic L, Doyle FJ. A Run-To-Run Framework for Prandial Insulin Dosing: Handling Real-Life Uncertainty. International Journal of Robust and Nonlinear Control 17:1194-1213, 2007 (Published).
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6. Zisser H, Bevier WC, Jovanovic L. Restoring Euglycemia in the Basal State Using Continuous Glucose Monitoring in Subjects with type 1 Diabetes Mellitus. Diabetes Technol Ther 9:509-515, 2007 (Published).
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7. Firas H. El-Khatib, John Jiang, Edward R. Damiano. Adaptive Closed-Loop Control Provides Blood-Glucose Regulation Using Dual Subcutaneous Insulin and Glucagon Infusion in Diabetic Swine.. Journal of Diabetes Science and Technology, March 2007, Volume 1, Issue 2: Page 181 - 192. (Published).
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8. El-Khatib FH, Jiang J, Gerrity RG, Damiano ER. Pharmacodynamics and stability of subcutaneously infused glucagon in a type 1 diabetic Swine model in vivo. Diabetes Technol Ther. 2007 Apr;9(2):135-44 (Published).
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9. Doyle F, Jovanovic L, Seborg D. Glucose Control Strategies for Treating Type 1 Diabetes Mellitus. Journal of Process Control 17: 572-576, 2007 (Published).
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10. Palerm CC and Bequette BW. Hypoglycemia Detection and Prediction Using Continuous Glucose Monitoring- A Study on Hypoglycemic Clamp Data. J Diabetes Sci Technol 1:617-623, 2007 (Published).
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11. Magni L, Raimondo DM, Bossi L, Dalla Man C, De Nicolao G, Kovatchev B, Cobelli C. Model Predictive Control of Type 1 Diabetes: An In Silico Trial. J Diabetes Sci Technol 1:804-812, 2007 (Published).
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12. Patek SD, Breton MD, Chen Y, Solomon C, Kovatchev B. Linear Quadratic Gaussian-Based Closed-Loop Control of Type 1 Diabetes. J Diabetes Sci Technol 1:834-841, 2007 (Published).
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13. Hovorka R. The Future for Closed-loop Insulin Delivery. Diabetes Digest 7:4-5, 2008 (Published).
(Manuscript)  
 
14. Hovorka R. The Future of Continuous Glucose Monitoring: Closed Loop. Current Diabetes Reviews 4:269-279, 2008 (Published).
(Manuscript)  
 
15. Marchetti G, Barolo M, Jovanovic L, Zisser H, Seborg DE. A Feedforward-Feedback Glucose Control Strategy for Type 1 Diabetes Mellitus. Journal of Process Control 18:149-162, 2008 (Published).
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16. Pennant ME, Bluck LJ, Marcovecchio ML, Salgin B, Hovorka R, Dunger DB. Insulin Administration and Rate of Glucose Appearance in People with Type 1 Diabetes. Diabetes Care. 2008 Nov;31(11):2183-7. doi: 10.2337/dc08-0705. Epub 2008 Jul 23 (Published).
(Manuscript) |  View Publication  
 
17. Wilinska E and Hovorka R. Simulation models for in silico testing of closed-loop glucose controllers in type 1 diabetes. Drug Discov Today Dis Models 5:289-298, 2008 (Published).
(Manuscript) |  View Publication  
 
18. Dassau E, Bequette BW, Buckingham BA, Doyle FJ. Detection of a Meal Using Continuous Glucose Monitoring: Implications for an Artificial Beta-Cell. Diabetes Care. 2008 Feb;31(2):295-300. Epub 2007 Oct 31 (Published).
(Manuscript) |  View Publication  
 
19. DeVries JH. Combining insulin pumps and continuous glucose monitors; where are we to go from here?. J Diabetes Sci Technol. 2008 Mar;2(2):261-2 (Published).
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20. Percival MW, Zisser H, Jovanovic L, Doyle III FJ. Closed-Loop Control and Advisory Mode Evaluation of an Artificial Pancreatic B-Cell: Use of Proportional-Integral-Derivative Equivalent Model-Based Controllers. J Diabetes Sci Technol 2:636-644, 2008 (Published).
(Manuscript)  
 
21. Weinzimer SA, Steil GM, Swan KL, Dziura J, Kurtz N, Tamborlane WV. Fully automated closed-loop insulin delivery versus semiautomated hybrid control in pediatric patients with type 1 diabetes using an artificial pancreas. Diabetes Care. 2008 May;31(5):934-9 (Published).
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22. Dassau E, Zisser H, Palerm CC, Buckingham BA, Jovanovic L, Doyle FJ. Modular Artificial B-Cell System: A Prototype for Clinical Research. J Diabetes Sci Technol 2:863-872, 2008 (Published).
(Manuscript)  
 
23. Bevier WC, Zisser H, Jovanovic L, Finan DA. Use of Continuous Glucose Monitoring to Estimate Insulin Requirements in Patients with Type 1 Diabetes Mellitus During a Short Course of Prednisone. J Diabetes Sci Technol 2:578-583, 2008 (Published).
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24. Cameron F, Niemeyer G, Gundy-Burlet K, Buckingham B. Statistical Hypoglycemia Prediction. J Diabetes Sci Technol 2:612-621, 2008 (Published).
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25. DeVries JH. Glucose sensing issues for the artificial pancreas.. J Diabetes Sci Technol. 2008 Jul;2(4):732-4 (Published).
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26. Ward WK. A Review of the Foreign-body Response to Subcutaneously-implanted Devices: The Role of Macrophages and Cytokines in Biofouling and Fibrosis. Journal of Diabetes Science and Technology Volume 2, Issue 5, September 2008 (Published).
(Manuscript) |  View Publication  
 
27. Bondia J, Dassau E, Zisser H, Calm R, Vehi J, Jovanovic L, Doyle III FJ. Coordinated basal-bolus infusion for tighter postprandial glucose control in insulin pump therapy. J Diab Sci Technol 3:89-97, 2009 (Published).
(Manuscript) |  View Publication  
 
28. Lee H and Bequette BW. A Closed-loop Artificial Pancreas based on MPC: human-friendly identification and automatic meal disturbance rejection. Biomedical Signal Processing and Control 4:347-354, 2009 (Published).
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29. Patek SD, Bequette BW, Breton M, Buckingham BA, Dassau E, Doyle FJ, Lum J, Magni L, Zisser H. In Silico Preclinical Trials: Methodology and Engineering Guide to Closed-Loop Control. J Diabetes Sci Technol 3:269-282, 2009 (Published).
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30. Percival MW, Dassau E, Zisser H, Jovanovic L, Doyle III FJ. Practical approach to design and implementation of a control algorithm in an artificial pancreatic beta cell. Ind. Eng. Chem. Res., 2009: 48, 6059-6067 (Published).
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31. Buckingham BA, Corby E, Clinton P, Gage V, Caswell K, Kunselman E, Cameron F, Chase HP.. Preventing Hypoglycemia Using Predictive Alarm Algorithms and Insulin Pump Suspension. Diabetes Technol Ther. 2009 Feb;11(2):93-7 (Published).
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32. Dassau E, Palerm CC, Zisser H, Buckingham BA, Jovanovic L, Doyle FJ. In Silico Evaluation Platform for Artificial Pancreatic ß-Cell Development—A Dynamic Simulator for Closed-Loop Control with Hardware-in-the-Loop. Diabetes Technol Ther 11:187-194, 2009 (Published).
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33. Ellingsen C, Dassau E, Percival MW, Zisser H, Jovanovic L, Doyle FJ. Safety constraints in artificial beta cell: An implementation of model predictive control with insulin-on-board. J Diabetes Sci Technol. 2009 May 1;3(3):536-44 (Published).
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34. Finan DA, Palerm CC, Doyle III FJ, Seborg DE, Zisser H, Bevier WC, Jovanovic L. Effect of input excitation on the quality of empirical dynamic models for type 1 diabetes. AIChEJ 2009; 55(5): 1135-1146 (Published).
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35. Zisser H, Palerm CC, Bevier WC, Doyle III FJ, Jovanovic L. Clinical update on optimal prandial insulin dosing using a refined run-to-run algorithm. J Diab Sci Technol 2009; 3 (3), 487-491 (Published).
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36. Clarke W, Kovatchev B. Statistical Tools to Analyze Continuous Glucose Monitor Data. Diabetes Technol Ther 11:S-45-S-54, 2009 (Published).
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37. Kumareswaran K, Evans ML, Hovorka R. Artificial pancreas: an emerging approach to treat Type 1 diabetes. Expert Rev Med Devices 6:401-410, 2009 (Published).
(Manuscript) |  View Publication  
 
38. Bequette BW. Glucose Clamp Algorithms and Insulin Time-Action Profiles. J Diabetes Sci Technol 3:1005-1013, 2009 (Published).
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39. Bruttomesso D, Farret A, Costa S, Marescotti MC, Vettore M, Avogaro A, Tiengo A, Dalla Man C, Place J, Facchinetti A, Guerra S, Magni L, De Nicolao G, Cobelli C, Renard E, Maran A. Closed-Loop Artificial Pancreas Using Subcutaneous Glucose Sensing and Insulin Delivery and a Model Predictive Control Algorithm: Preliminary Studies in Padova and Montpellier. J Diabetes Sci Technol 3:1014-1021, 2009 (Published).
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40. Cameron F, Niemeyer G, Buckingham B. Probabilistic Evolving Meal Detection and Estimation of Meal Total Glucose Appearance.. J Diabetes Sci Technol. 2009 Sep 1;3(5):1022-30. (Published).
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41. Cengiz E, Swan KL, Tamborlane WV, Steil GM, Steffen AT, Weinzimer SA. Is an automatic pump suspension feature safe for children with type 1 diabetes? An exploratory analysis with a closed-loop system. Diabetes Technol Ther 11:207-210, 2009 (Published).
(Manuscript) |  View Publication  
 
42. Finan DA, Doyle FJ, Palerm CC, Bevier WC, Zisser HC, Jovanovic L, Seborg DE. Experimental Evaluation of a Recursive Model Identification Technique for Type 1 Diabetes. J Diabetes Sci Technol. 2009 Sep 1;3(5):1192-202 (Published).
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43. Kanderian SS, Voskanyan G, Steil G. Identification of Intraday Metabolic Profiles during Closed-Loop Glucose Control in Individuals with Type 1 Diabetes. J Diabetes Sci Technol 3:1047-1057, 2009 (Published).
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44. Klonoff DC, Cobelli C, Kovatchev B, Zisser H. Progress in Development of an Artificial Pancreas. J Diabetes Sci Technol. 2009 Sep 1;3(5):1002-4. (Published).
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45. Kovatchev B, Patek S, Dassau E, Doyle FJI, Magni L, De Nicolao G, Cobelli C, the Juvenile Diabetes Research Foundation Artificial Pancreas Consortium. Control to Range for Diabetes: Functionality and Modular Architecture. J Diabetes Sci Technol 3:1058-1065, 2009 (Published).
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46. Kowalski A, Lum JW. Can We Really Close the Loop and How Soon? Accelerating the Availability of an Artificial Pancreas: A Roadmap to Better Diabetes Outcomes. J Diabetes Sci Technol 3:1224-1226, 2009 (Published).
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47. Lee H, Buckingham B, Wilson DM, Bequette BW. A Closed-Loop Artificial Pancreas Using Model Predictive Control and a Sliding Meal Size Estimator. J Diabetes Sci Technol 3:1082-1090, 2009 (Published).
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48. Magni L, Forgione M, Toffanin C, Dalla man C, Kovatchev B, De Nicolao G. Run-to-Run Tuning of Model Predictive Control for Type 1 Diabetes Subjects: In Silico Trial. J Diabetes Sci Technol. 2009 Sep 1;3(5):1091-8. (Published).
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49. Wang Y, Percival MW, Dassau E, Zisser HC, Jovanovic L, Doyle FJ. A Novel Adaptive Basal Therapy Based on the Value and Rate of Change of Blood Glucose. J Diabetes Sci Technol 5:1099-1108, 2009 (Published).
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50. Wilinska ME, Budiman ES, Taub MB, Elleri D, Allen JM, Acerini CL, Dunger DB, Hovorka R. Overnight Closed-Loop Insulin Delivery with Model Predictive Control: Assessment of Hypoglycemia and Hyperglycemia Risk Using Simulation Studies. J Diabetes Sci Technol 3:1109-1120, 2009 (Published).
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51. Dassau E, Jovanovic L, Doyle FJ, Zisser HC. Enhanced 911/global position system wizard: A telemedicine application for the prevention of severe hypoglycemia – monitor, alert, and locate. J Diabet Sci Technol 2009;3(6):1501-1506 (Published).
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52. Wang Y, Gao F, Doyle FJ III. Francis J. Doyle III. Survey on iterative learning control, repetitive control, and run-to-run control. Journal of Process Control Volume 19, Issue 10, December 2009, Pages 1589–1600 (Published).
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53. Ward WK, Duman HM. Strategies to Overcome Biological Barriers to Biosensing. J Diabetes Sci Technol, 2009 (Published).
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54. Cobelli C, Dalla Man C, Sparacino G, Magni L, De Nicolao G, Kovatchev B. Diabetes: Models, Signals, and Control. EEE Trans Biomed Eng 2, 2009 (Published).
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55. Castle, J and WK Ward. Amperometric Glucose Sensors: Sources of Error and Potential Benefit of Redundancy. J Diabetes Sci Technol. 2010 Jan 1;4(1):221-5 (Published).
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56. Wang Y, Zisser H, Dassau E, Jovanovic L, Doyle FJ III. Model predictive control with learning-type set-point: Application to artificial pancreatic ?-cell. AIChE J 2010; 56: 1510-1518 (Published).
(Manuscript)  
 
57. Wei C, Lunn DJ, Acerini CL, Allen JM, Larsen AM, Wilinska ME, Dunger DB, Hovorka R. Measurement delay associated with the Guardian® RT continuous glucose monitoring system. Diabet Med 27:117-122, 2010 (Published).
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58. Wilinska ME, Chassin LJ, Acerini CL, Allen JM, Dunger DB, Hovorka R. Simulation Environment to Evaluate Closed-Loop Insulin Delivery Systems in Type 1 Diabetes. J Diabetes Sci Technol 4:132-144, 2010 (Published).
(Manuscript)  
 
59. Zisser HC, Bevier W, Dassau E, Jovanovic L. Siphon effects on continuous subcutaneous insulin infusion pump delivery performance. J Diab Sci Technol 2010; 4:98-103 (Published).
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60. Hovorka R, Allen JM, Elleri D, Chassin LJ, Harris J, Xing D, Kollman C, Hovorka T, Larsen AM, Nodale M, De Palma A, Wilinska ME, Acerini CL, Dunger DB. Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial. Lancet. 2010 Feb 27;375(9716):743-51. doi: 10.1016/S0140-6736(09)61998-X. Epub 2010 Feb 4. (Published).
(Manuscript) |  View Publication  
 
61. Bequette BW. Continuous Glucose Monitoring: Real-Time Algorithms for Calibration, Filtering, and Alarms. J Diabetes Sci Technol 4:404-418, 2010 (Published).
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62. Cobry E, McFann K, Messer L, Gage V, VanderWel B, Horton L, Chase HP. Timing of Meal Insulin Boluses to Achieve Optimal Postprandial Glycemic Control in Patients with Type 1 Diabetes. Diabetes Technol Ther 12:173-177, 2010 (Published).
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63. Harvey RA, Wang Y, Grosman B, Percival MW, Bevier W, Finan DA, Zisser H, Seborg DE, Jovanovic L, Doyle FJ III, Dassau E. The quest for the artificial pancreas: Combining technology with treatment. IEEE Eng Med Biol Med 2010; March/April: 53-62 (Published).
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64. El-Khatib FH, Russell SJ, Nathan DM, Sutherlin RG, Damiano ER. A Bihormonal Closed-Loop Artificial Pancreas for Type 1 Diabetes. Sci Transl Med 2:27ra27, 2010 (Published).
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65. van Bon AC, Kohinor MJ, Hoekstra JB, von Basum G, deVries JH. Patients' perception and future acceptance of an artificial pancreas. J Diabetes Sci Technol. 2010 May 1;4(3):596-602 (Published).
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66. Dassau E, Cameron F, Lee H, Bequette BW, Zisser H, Jovanovic L, Chase HP, Wilson DM, Buckingham BA, and Doyle FJ. Real-Time Hypoglycemia Prediction Suite Using Continuous Glucose Monitoring: A safety net for the artificial pancreas. Diabetes Care 2010, 33:1249-1254 (Published).
(Manuscript) |  View Publication  
 
67. Hovorka R. Reducing risk and severity of hypoglycemia with closed loop insulin delivery in type 1 diabetes: from dream to reality. Diabetic Hypoglycemia 3 (1):3-7, 2010 (Published).
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68. Grosman B, Dassau E, Zisser HC, Jovanovic L, Doyle FJ III. Zone model predictive control: A strategy to minimize hyper- and hypoglycemic events. J Diabet Sci Technol 2010; 4: 961-75 (Published).
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69. Mauseth R, Wang Y, Dassau E, Kircher R, Matheson D, Zisser H, Jovanovic L, Doyle F. Proposed clinical application for tuning fuzzy logic controller of artificial pancreas utilizing a personalization factor. J Diabetes Sci Technol 4:913-922, 2010 (Published).
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70. van Bon AC, Hermanides J, Koops R, Hoekstra JB, DeVries JH. Postprandial glycemic excursions with the use of a closed-loop platform in subjects with type 1 diabetes: a pilot study. J Diabetes Sci Technol. 2010 Jul 1;4(4):923-8 (Published).
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71. Ward WK, Hansen JC, Massoud RG, Engle JM, Takeno MM, Hauch KD. Controlled Release of Dexamethasone from Subcutaneously-implanted Biosensors in Pigs: Localized Anti-inflammatory Benefit without Systemic Effects. J Biomed Mater Res A. 2010 Jul;94(1):280-7. doi: 10.1002/jbm.a.32651 (Published).
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72. Percival MW, Bevier WC, Wang Y, Dassau E, Zisser H, Jovanovic L, Doyle FJ III. Modeling the Effects of Subcutaneous Insulin Administration and Carbohydrate Consumption on Blood Glucose. J Diabet Sci Technol 2010; 4(5):1214-1228 (Published).
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73. Castle JR, Engle JM, El Youssef J, Massoud RG, Ward WK. Factors influencing the effectiveness of Glucagon for preventing hypoglycemia. J Diabet Sci Technol 2010; 4: 1305-1310 (Published).
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74. Dassau E, Atlas E, Phillip M. Closing the Loop. Int J Clin Pract Suppl. 2010 Feb;(166):20-5. (Published).
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75. El Youssef J, Castle J, Engle J, Massoud RG, Ward WK. Continuous Glucose Monitoring in Subjects with Type 1 Diabetes: Improvement in Accuracy by Correcting for Background Current. Diabetes Technol Ther. 2010 Nov;12(11):921-8 (Published).
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76. Kovatchev B, Cobelli C, Renard E, Anderson S, Breton M, Patek S, Clarke W, Bruttomesso D, Maran A, Costa S, Avogaro A, Dalla Man C, Facchinetti A, Magni L, De Nicolao G, Place J, Farret A. Multinational study of subcutaneous model-predictive closed-loop control in type 1 diabetes mellitus: Summary of results. J Diabet Sci Technol 2010; 4: 1374-1381 (Published).
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77. Russell SJ, El-Khatib FH, Nathan DM, Damiano ER. Efficacy determinants of subcutaneous microdose glucagon during closed-loop control. J Diabet Sci Technol 2010; 4: 1288-1304 (Published).
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78. Ward WK, Massoud RG, Szybala CJ, Engle JM, El Youssef J, Carroll JM, Roberts CT, DiMarchi RD. In vitro and in vivo evaluation of native glucagon and glucagon analog (MAR-D28) during aging: Lack of cytotoxicity and preservation of hyperglycemic effect. J Diabetes Sci Technol. 2010 Nov 1;4(6):1311-21 (Published).
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79. Murphy H.R., Elleri D., Allen J.M., Harris J., Simmons D., Rayman G., Temple R., Dunger D.B., Haidar A., M. Nodale, M. E. Wilinska, and R. Hovorka. Closed-loop insulin delivery during pregnancy complicated by type 1 diabetes. Diabetes Care 34 (2):406-411, 2011 (Published).
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80. Hovorka R.. Closed-loop insulin delivery: from bench to clinical practice. Nat.Rev.Endocrinol. doi:10.1038/nrendo.2011.32, 2011 (Published).
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81. Cameron F, Bequette BW, Wilson DM, Buckingham BA, Lee H, Niemeyer G. A Closed-Loop Artificial Pancreas Based on Risk Management. J Diabetes Sci Technol 2011; 5(2):368-379 (Published).
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82. Kovatchev B. Monitoring, Assessment, and Control of Blood Glucose Fluctuations in Diabetes. Treatment Strategies- Diabetes (Published).
(Manuscript)  
 
83. Elleri D., Allen J. M., Nodale M., Wilinska M. E., Mangat J. S., Larsen A. M., Acerini C. L., Dunger D. B., and Hovorka R.. Automated overnight closed-loop glucose control in young children with type 1 diabetes. Diabetes Technol.Ther. 2011; 13 (4):419-424 (Published).
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84. Hovorka R, Kumareswaran K, Harris J, Allen JM, Elleri D, Xing D, Kollman C, Nodale M, Murhpy HR, Dunger DB, Amiel SA, Heller SR, Wilinska ME, Evans ML. Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies. BMJ 2011;342: 1855 (Published).
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85. Kovatchev B. Closed loop control for type 1 diabetes: Shows promise in a research setting, but needs further development in practice. BMJ 2011; 342:d1911 doi:10.1136/bmj.d1911 (Published).
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86. King L.H., Realsen J., Cobry E., Chase H.P.. The Need for an Ultra-Rapid Acting Insulin. Infusystems USA 2011; 8(1):1-5 (Published).
(Manuscript)  
 
87. Beck RW, Kollman C, Xing D, Buckingham BA, Chase HP. Outcome Measures for Outpatient Hypoglycemia Prevention Studies. J Diabetes Sci Technol. 2011 Jul 1;5(4):999-1004 (Published).
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88. Cengiz E, Sherr JL, Weinzimer SA, Tamborlane WV. New-generation diabetes management: glucose sensor-augmented insulin pump therapy. Expert Rev Med Devices. 2011 July; 8(4): 449–458 (Published).
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89. van Bon AC, Brouwer TB, von Basum G, Hoekstra JB, DeVries JH. Future acceptance of an artificial pancreas in adults with type 1 diabetes. Diabetes Technol Ther. 2011 Jul;13(7):731-6 (Published).
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90. Zisser, H.. Clinical Hurdles and Possible Solutions in the Implementation of Closed-Loop Control in Type 1 Diabetes Mellitus. J Diabetes Sci Technol. 2011 Sep 1;5(5):1283-6 (Published).
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91. Miller S., Nimri R., Atlas E., Grunberg E.A., Phillip M.. Automatic Learning Algorithm for the MD-Logic Artificial Pancreas System. Diabetes Technol Ther 2011 Oct; 13(10):983-90 (Published).
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92. Cobello, C., Renard, E., Kovatchev, B. Artificial Pancreas: Past, Present, Future. Diabetes 2011 Nov; 60(11): 2672-2682. http://dx.doi.org/10.2337/db11-0654 (Published).
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93. Heinemann L, Benesch C, DeVries JH. AP@home: a novel European approach to bring the artificial pancreas home. J Diabetes Sci Technol. 2011 Nov 1;5(6):1363-72 (Published).
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94. Zisser H., Breton M., Dassau E., Markova K., Bevier W., Seborg D., Kovatchev B.. Novel methodology to determine the accuracy of the OmniPod insulin pump: a key component of the artificial pancreas system.. J Diabetes Sci Technol. 2011 Nov 1;5(6):1509-18. (Published).
(Manuscript) |  View Publication  
 
95. Realsen J.M., Chase H.P.. Recent Advances in the Prevention of Hypoglycemia in Type 1 Diabetes. Diabetes Technol Ther. 2011 Dec;13(12):1177-86. (Published).
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96. Ward, K.W., Engle, J.M., Branigan, D., Youssef, J.El., Massoud, R.G., Castle, J.R.. The effect of rising vs. falling glucose level on amperometric glucose sensor lag and accuracy in Type 1 diabetes. Diabet Med. 2011 Dec 12. doi: 10.1111/j.1464-5491.2011.03545.x. (Published).
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97. K. Kumareswaran, D. Elleri, J. M. Allen, J. Harris, D. Xing, C. Kollman, M. Nodale, H. R. Murphy, S. A. Amiel, S. R. Heller, M. E. Wilinska, C. L. Acerini, M. L. Evans, D. B. Dunger, and R. Hovorka.. Meta-analysis of overnight closed-loop randomized studies in children and adults with type 1 diabetes: the Cambridge cohort.. Diabetes Sci.Technol. 5 (6):1352-1362, 2011. (Published).
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98. Kanderian S, Weinzimer S.A., Steil G.M.. The Identifiable Virtual Patient Model – Comparison of Simulation and Clinical Closed-loop Study Results.. J Diabetes Sci Technol March 2012 vol. 6 no. 2 371-379 (Published).
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99. Kumareswaran, K., Evans M.L., Hovorka R.. Closed-loop insulin delivery: towards improved diabetes care.. Discov.Med. 13 (69):159-170, 2012. (Published).
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100. Haidar, A., Elleri D., Allen, J., Harris, J., Kumareswaran, K., Nodale, M., Acerini C., Wilinska M., Jackson, N., Umpleby, M., Evans, M. L., Dunger D., and Hovorka, R.. Validity of Triple and Dual-Tracer Techniques to Estimate Glucose Appearance. American Journal of Physiology - Endocrinology and Metabolism Published 15 June 2012 Vol. 302 no. 12, E1493-E1501 (Published).
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101. Thabit, H., Hovorka, R.. Closed-loop insulin delivery in type 1 diabetes. Endocrinol.Metab Clin.North Am. 41 (1):105-117, 2012 (Published).
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102. Breton M, Farret A, Bruttomesso D, Anderson S, Magni L, Patek S, Dalla Man C, Place J, Demartini S, Del Favero S, Toffanin C, Hughes-Karvetski C, Dassau E, Zisser H, Doyle FJ 3rd, De Nicolao G, Avogaro A, Cobelli C, Renard E, Kovatchev B; on behalf of The International Artificial Pancreas (iAP) Study Group.. Fully-integrated artificial pancreas in type 1 diabetes: modular closed-loop glucose control maintains near-normoglycemia. Diabetes. 2012 Sep;61(9):2230-2237 (Published).
(Manuscript) |  View Publication  
 
103. Sun J, Cameron, F., Bequette, B.W.. Habituating Multiple Model Predictive Control for Blood Glucose Regulation in the ICU. 2012 American Control Conference, Montreal (June 2012) pp. 3509-3515 (Published).
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104. Cengiz E. Undeniable Need for Ultrafast-Acting Insulin: The Pediatric Perspective. J Diabetes Sci Technol 2012;6(4):797-801 (Published).
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105. Weinzimer, S.A., Sherr, J.L., Cengiz, E., Kim, G., Ruiz, J.L., Carria, L., Voskanyan, G., Roy, A., Tamborlane, W.V.. Effect of Pramlintide on Prandial Glycemic Excursions During Closed-Loop Control in Adolescents and Young Adults With Type 1 Diabetes. Diabetes Care. 2012 Oct;35(10):1994-9 (Published).
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106. Weinzimer SA. Continuous glucose monitoring in young children: satisfaction without success?. Diabetes Technol Ther 2012 Sep;14(9):753-5 (Published).
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107. Cameron F, Niemeyer G, Bequette BW. Extended multiple model prediction with application to blood glucose regulation. J. Process Control, 2012;12(7):1422-1432 (Published).
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108. Cameron, F., Wilson, D.M., Buckingham, B.A., Arzumanyan, H., Clinton, P., Chase, P.H., Lum, J., Maahs, D.M., Calhoun, P.M., Bequette, B.W.. In-Patient Studies of a Kalman Filter based Predictive Pump Shut-off Algorithm. J. Diabetes Sci. Technol., 2012;6(5):1142-1147. (Published).
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109. Cobelli C, Renard E, Kovatchev BP, Keith-Hynes P, Brahim NB, Place J, Del Favero S, Breton M, Farret A, Bruttomesso D, Dassau E, Zisser H, Doyle FJ, Patek SD, Avogaro A. Pilot Studies of Wearable Outpatient Artificial Pancreas in Type 1 Diabetes. Diabetes Care. 2012 Sep;35(9):e65-e67 (Published).
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110. Sun J, Cameron, Bequette BW. A Habituating Blood Glucose Control Strategy for the Critically Ill. J. Process Control, 2012;22(7):1411-1421 (Published).
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111. Beck RW., Calhoun P., Kollman C. Use of Continuous Glucose Monitoring as an Outcome Measure in Clinical Trials. Diabetes Technol Ther. 2012 Oct;14(10):877-82. (Published).
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112. Bequette, B.W.. Challenges in the Development of a Closed-loop Artificial Pancreas. Annual Reviews in Control Volume 36, Issue 2, December 2012, Pages 255–266 (Published).
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113. Keenan D.B., Grosman B, Clark H.W., Roy A, Weinzimer S.A., Shah R.V., Mastrototaro, J.J.. Continuous Glucose Monitoring: Considerations for the Development of a Closed Loop Artificial Pancreas System.. J Diabetes Sci Technol. 2011 Nov 1;5(6):1327-36 (Published).
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114. O'Grady MJ, Retterath AJ, Keenan DB, Kurtz N, Cantwell M, Spital G, Kremliovsky MN, Roy A, Davis EA, Jones TW, Ly TT. The Use of an Automated, Portable, Glucose Control System for Overnight Glucose Control in Adolescents and Young Adults With Type 1 Diabetes. Diabetes Care November 2012 vol. 35 no. 11 2182-2187 (Published).
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115. Russel SJ., El-Khatib FH., Nathan DM., Magyar KL., Jiang J., Damiano ER.. Blood Glucose Control in Type 1 Diabetes With a Bihormonal Bionic Endocrine Pancreas. Diabetes Care November 2012 vol. 35 no. 11 2148-2155 (Published).
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116. Weinzimer SA. Closed-loop systems: diversity and natural selection. Diabetes Care November 2012 35:2111-2112 (Published).
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117. Wolpert HA, Atakov-Castillo A, Smith SA, Steil GM. Dietary Fat Acutely Increases Glucose Concentrations and Insulin Requirements in Patients W/ T1 Diabetes: implications for carbohydrate-based bolus dose calculation and intensive diabetes management.. Diabetes Care. 2013 Apr;36(4):810-6. doi: 10.2337/dc12-0092. Epub 2012 Nov 27. (Published).
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118. Jackson MA, Caputo N, Castle JR, David LL, Roberts, Jr. CT, Ward WK. Stable liquid glucagon formulations for rescue treatment and bi-hormonal closed-loop pancreas. Curr Diab Rep. 2012 Dec;12(6):705-10 (Published).
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119. Lee JJ., Dassau E., Zisser H., Harvey RA., Jovanovic L., Doyle FJ.. In Silico Evaluation of an Artificial Pancreas Combining Exogenous Ultrafast-Acting Technosphere Insulin with Zone Model Predictive Control. Journal of Diabetes Science and Technology, January 2013, Volume 7, Issue 1: pages 215–226 (Published).
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120. Facchinetti A, Sparacino G, Guerra S, Luijf YM, DeVries JH, Mader JK, Ellmerer M, Benesch C, Heinemann L, Bruttomesso D, Avogaro A, Cobelli C. Real-time improvement of continuous glucose monitoring accuracy: the smart sensor concept. Diabetes Care. 2013 Apr;36(4):793-800 (Published).
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121. Caputo N, Castle JR, Bergstrom CP, Carroll JM, Bakhtiani PA, Jackson MA, Roberts CT Jr, David LL, Ward WK. Mechanisms of glucagon degradation at alkaline pH.. Peptides. 2013 Jul;45:40-7 (Published).
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122. Stenvers DJ, DeVries JH, la Fleur SE. What's the Time? Does the Artificial Pancreas Need to Know?. Diabetes. 2013 Jul;62(7):2173-4 (Published).
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123. Micheletto F, Dalla Man C, Kolterman O, Chiquette E, Herrmann K, Schirra J, Kovatchev B, Cobelli C. In Silico Design of Optimal Ratio for Co-Administration of Pramlintide and Insulin in Type 1 Diabetes. Diabetes Technol Ther. 2013 Oct;15(10):802-9 (Published).
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124. Bequette B. Algorithms for a Closed-Loop Artificial Pancreas: The Case for Model Predictive Control. Diabetes Sci. Technol. 2013;7(6):1632-1643 (Published).
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125. Bakhtiani PA, Zhao LM, El Youssef J, Castle JR, Ward WK. A review of artificial pancreas technologies with an emphasis on bi-hormonal therapy. Diabetes Obes Metab. 2013 Dec;15(12):1065-70 (Published).
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126. Luijf YM, DeVries JH, Zwinderman K, Leelarathna L, Nodale M, Caldwell K, Kumareswaran K, Elleri D, Allen JM, Wilinska ME, Evans ML, Hovorka R, Doll W, Ellmerer M, Mader JK, Renard E, Place J, Farret A, Cobelli C, Del Favero S, Dalla Man C, Avogaro A, Bruttomesso D, Filippi A, Scotton R, Magni L, Lanzola G, Di Palma F, Soru P, Toffanin C, De Nicolao G, Arnolds S, Benesch C, Heinemann L. Day and night closed-loop control in adults with type 1 diabetes: a comparison of two closed-loop algorithms driving continuous subcutaneous insulin infusion versus patient self-management. Diabetes Care. 2013 Dec;36(12):3882-7. doi: 10.2337/dc12-1956. Epub 2013 Oct 29 (Published).
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127. DeSalvo DJ, Keith-Hynes P, Peyser T, Place J, Caswell K, Wilson DM, Harris B, Clinton P, Kovatchev B, Buckingham BA. Remote Glucose Monitoring in Camp Setting Reduces the Risk of Prolonged Nocturnal Hypoglycemia. Diabetes Technol Ther. 2014 Jan;16(1):1-7 (Published).
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128. Finan DA, McCann TW, Rhein K, Dassau E, Breton MD, Patek SD, Anhalt H, Kovatchev BP, Doyle FJ, Anderson SM, Zisser H, Venugopalan R. Closed-Loop Control Performance of the Hypoglycemia-Hyperglycemia Minimizer (HHM) System in a Feasibility Study. J Diabetes Sci Technol January 2014 vol. 8 no. 1 35-42 (Published).
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129. Patel PJ, Benasi K, Ferrari G, Evans MG, Shanmugham S, Wilson DM, Buckingham BA. Randomized Trial of Infusion Set Function: Steel Versus Teflon. Diabetes Technol Ther 2014 Jan;16(1):15-9 (Published).
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130. Ramkissoon C, Aufderheide B, Bequette B, Palerm C. A Model of Glucose-Insulin-Pramlintide Pharmacokinetics and Pharmacodynamics in Type I Diabetes. J Diabetes Sci Technol. 2014;8(3):529-542 (Published).
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131. Place J, Farret A, Del Favero S, Bruttomesso D, Renard E. Assessment of Patient Perceptions About Web Telemonitoring Applied to Artificial Pancreas Use at Home. J Diabetes Sci Technol. 2014 Mar 2;8(2):225-229 (Published).
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132. Beck RW, Raghinaru D, Wadwa RP, Chase HP, Maahs DM, Buckingham BA; In Home Closed Loop Study Group.. Frequency Of Morning Ketosis After Overnight Insulin Suspension Using An Automated Nocturnal Predictive Low Glucose Suspend System.. Diabetes Care. 2014 May;37(5):1224-9 (Published).
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133. Cefalu W, Tamborlane W. The Artificial Pancreas: Are We There Yet?. Diabetes Care. 2014 May;37(5):1182-1183 (Published).
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134. Doyle III F, Huyett L, Lee J, Zisser H, Dassau E. Closed-Loop Artificial Pancreas Systems: Engineering the Algorithms. Diabetes Care. 2014 May;37(5):1191-1197 (Published).
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135. Favero S, Bruttomesso D, Palma F, Lanzola G, Visentin R, Filippi A, Scotton R, Toffanin C, Messori M, Scarpellini S, Keith-Hynes P, Kovatchev B, DeVries J, Renard E, Magni L, Avogaro A, Cobelli C, and on behalf of the AP@home Consortium. First Use of Model Predictive Control in Outpatient Wearable Artificial Pancreas. Diabetes Care. 2014 May;37(5):1212-1215 (Published).
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136. Hovorka R, Elleri D, Thabit H, Allen J, Leelarathna L, El-Khairi R, Kumareswaran K, Caldwell K, Calhoun P, Kollman C, Murphy H, Acerini C, Wilinska M, Nodale M, and Dunger D. Overnight Closed-Loop Insulin Delivery in Young People With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial. Diabetes Care. 2014 May;37(5):1204-1211 (Published).
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137. Kudva Y, Carter R, Cobelli C, Basu R, Basu A. Closed-Loop Artificial Pancreas Systems: Physiological Input to Enhance Next-Generation Devices. Diabetes Care. 2014 May;37(5):1184-1190 (Published).
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138. Kumareswaran K, Thabit H, Leelarathna L, Caldwell K, Elleri D, Allen J, Nodale M, Wilinska M, Evans M, Hovorka R. Feasibility of Closed-Loop Insulin Delivery in Type 2 Diabetes: A Randomized Controlled Study. Diabetes Care. 2014 May;37(5):1198-1203 (Published).
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139. Schiavon M, Man C, Kudva Y, Basu A, Cobelli1 C. Quantitative Estimation of Insulin Sensitivity in Type 1 Diabetic Subjects Wearing a Sensor-Augmented Insulin Pump. Diabetes Care. 2014 May; 37(5):1216-1223 (Published).
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140. Thabit H, Kumareswaran K, Haidar A, Leelarathna L, Caldwell K, Elleri D, Allen J, Nodale M, Wilinska ME, Jackson NC, Umpleby AM, Evans ML, Hovorka R. Glucose turnover after replacement of usual therapy by insulin in insulin-naive type 2 diabetes subjects. J Clin Endocrinol Metab 2014 Jun; 99(6):2225-32 (Published).
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141. Kovatchev* BP, Renard E, Cobelli C, Zisser H, Keith-Hynes P, Anderson SM, Brown SA, Chernavvsky DR, Breton MD, Mize LB, Farret A, Place J, Bruttomesso D, Del Favero S, Boscari F, Galasso S, Avogaro A, Magni L, DiPalma F, Toffanin C, Messori M, Dassau E, Doyle FJ. Safety of Outpatient Closed-Loop Control: First Randomized Cross-Over Trials of a Wearable Artificial Pancreas. Diabetes Care. 2014 Jul;37(7):1789-96 (Published).
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142. Leelarathna L, Dellweg S, Mader JK, Allen JM, Benesch C, Doll W, Ellmerer M, Hartnell S, Heinemann L, Kojzar H, Michalewski L, Nodale M, Thabit H, Wilinska ME, Pieber TR, Arnolds S, Evans ML, Hovorka R. Day and night home closed-loop insulin delivery in adults with type 1 diabetes: three-center randomized crossover study. Diabetes Care 2014 Jul;37(7):1931-7 (Published).
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143. Maahs DM, Calhoun P, Buckingham BA, Chase HP, Hramiak I, Lum J, Cameron F, Bequette BW, Aye T, Paul HT, Slover R, Wadwa P, Wilson DM, Kollman C, Beck RW. A Randomized Trial Of A Home System To Reduce Hypoglycemia In Type 1 Diabetes. J Diabetes Sci Technol. 2014;8(3):529-542 (Published).
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144. Nimri R, Muller I, Atlas E, Miller S, Fogel A, Bratina N, Kordonouri O, Battelino T, Danne T, Phillip M. MD-Logic Overnight Control for 6 Weeks of Home Use in Patients With Type 1 Diabetes: Randomized Crossover Trial. Diabetes Care. 2014 Jul. 37(11): 3025-3032 (Published).
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145. Breton* MD, Brown SA, Hughes-Karvetski C, Kollar L, Topchyan KA, Anderson SM, Kovatchev BP. Adding heart rate signal to a control-to-range artificial pancreas system improves the protection against hypoglycemia during exercise in type 1 diabetes. Diabetes Technology & Therapeutics. July 2014, 16(8): 506-511. doi:10.1089/dia.2013.0333. (Published).
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146. Ly TT, Breton MD, Keith-Hynes P, De Salvo D, Clinton P, Benassi K, Mize B, Chernavvsky D, Place J, Wilson DM, Kovatchev BP, Buckingham BA. Overnight glucose control with an automated, unified safety system in children and adolescents with type 1 diabetes at diabetes cAMP. Diabetes Care. 2014 Aug;37(8):2310-6 (Published).
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147. Nimri R, Phillip M. Artificial Pancreas: Fuzzy Logic and Control of Glycemia. Current Opinion in Endocrinology, Diabetes and Obesity. 2014 Aug. 21(4): 251-256 (Published).
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148. Del Favero, S., Magni, L., Kovatchev, B., Cobelli, C. From In- to Out-patient Artificial Pancreas Studies: Results And New Developments. Preprints of the 19th World Congress The International Federation of Automatic Control Cape Town, South Africa. August 24-29, 2014 (Published).
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149. Messori, M., Fornasiero, E., Toffanin, C., Cobelli, C., Magni, L. A Constrained Model Predictive Controller for an Artificial Pancreas. IFAC Proceedings Volumes Volume 47, Issue 3, 2014, Pages 10144–10149 19th IFAC World Congress (Published).
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150. Cobelli C, Renard E, Kovatchev B. The artificial pancreas: a digital-age treatment for diabetes. Lancet Diabetes Endocrinol. 2014 Sep;2(9):679-81 (Published).
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151. DeSalvo DJ, Shanmugham S, Ly TT, Wilson DM, Buckingham BA. Accuracy evaluation of blood glucose monitoring systems in children on overnight closed-loop control. J Diabetes Sci Technol. 2014 Sep;8(5):969-73 (Published).
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152. Thabit H, Lubina-Solomon A, Stadler M, Leelarathna L, Walkinshaw E, Pernet A, Allen JM, Iqbal A, Choudhary P, Kumareswaran K, Nodale M, Nisbett C, Wilinska ME, Dunger DB, Heller SR, Amiel SA, Evans ML, Hovorka R. Home use of closed loop insulin delivery improves overnight glucose control in adults with type 1 diabetes: A four-week multicentre randomised crossover study. Lancet Diabetes Endocrinol. 2014 Sep;2(9):701-9 (Published).
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153. Leelarathna L, Dellweg S, Mader JK, Barnard K, Benesch C, Ellmerer M, Heinemann L, Kojzar H, Thabit H, Wilinska ME, Wysocki T, Pieber TR, Arnolds S, Evans ML, Hovorka R. Assessing the effectiveness of 3 months day and night home closed-loop insulin delivery in adults with suboptimally controlled type 1 diabetes: a randomised crossover study protocol. BMJ Open. 2014 Sep 3;4(9):e006075 (Published).
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154. Bevier WC, Fuller SM, Fuller RP, Rubin RR, Dassau E, Doyle FJ 3rd, Jovanovic L, Zisser HC. Artificial Pancreas (AP) Clinical Trial Participants' Acceptance Of Future AP Technology.. Diabetes Technol Ther. 2014 Sep;16(9):590-5 (Published).
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155. Chase HP, Doyle FJ 3rd, Zisser H, Renard E, Nimri R, Cobelli C, Buckingham BA, Maahs DM, Anderson S, Magni L, Lum J, Calhoun P, Kollman C, Beck RW; Control to Range Study Group.. Multicenter Closed-Loop/Hybrid Meal Bolus Insulin Delivery With Type 1 Diabetes. Diabetes Technol Ther. 2014 Oct;16(10):623-32 (Published).
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156. Zisser H, Renard E, Kovatchev B, Cobelli C, Avogaro A, Nimri R, Magni L, Buckingham BA, Chase HP, Doyle FJ 3rd, Lum J, Calhoun P, Kollman C, Dassau E, Farret A, Place J, Breton M, Anderson SM, Dalla Man C, Del Favero S, Bruttomesso D, Filippi A, Scotton R, Phillip M, Atlas E, Muller I, Miller S, Toffanin C, Raimondo DM, De Nicolao G, Beck RW; Control to Range Study Group.. Multicenter Closed-Loop Insulin Delivery Study Points To Challenges For Keeping Blood Glucose In A Safe Range By A Control Algorithm In Adults And Adolescents With Type 1 Diabetes From Various Sites. Diabetes Technol Ther. 2014 Oct;16(10):613-22 (Published).
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157. Baysal N, Cameron F, Buckingham BA, Wilson DM, Chase HP, Maahs DM, Bequette BW; In Home Closed-Loop Study Group (IHCL). A Novel Method to Detect Pressure-Induced Sensor Attenuations (PISA) in an Artificial Pancreas. J Diabetes Sci Technol. 2014 Nov;8(6):1091-6 (Published).
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158. Cameron F, Niemeyer G, Wilson DM, Bequette BW, Benassi KS, Clinton P, Buckingham BA. Inpatient Trial of an Artificial Pancreas Based on Multiple Model Probabilistic Predictive Control with Repeated Large Unannounced Meals. Diabetes Technology & Therapeutics. October 2014, 16(11): 728-734. doi:10.1089/dia.2014.0093. (Published).
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159. Cameron, F., Ly, T.T., Forlenza, G.P., Patek, S.D., Baysal, N., Messer, L.H., Clinton, P., Maahs, D.M., Buckingham, B.A. and Bequette, B.W.. Inpatient Clinical Trial of a Fully Closed-Loop Artificial Pancreas Using Only CGM and Acceleromter Data for Insulin Dosing. Diabetes Technol Ther. 2014 Nov 1; 16(11): 728–734 (Published).
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160. Oron T, Farfel A, Muller I, Atlas E, Nimri R, Phillip M. A Remote Monitoring System for Artificial Pancreas Support Is Safe, Reliable, and User Friendly. Diabetes Technology & Therapeutics. October 2014, 16(11): 699-705. doi:10.1089/dia.2014.0090. (Published).
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161. Haidar A, Legault L, Messier V, Mitre T, Leroux C, Rabasa-Lhoret R. Comp of D-H Artificial Pancreas, S-H Artificial Pancreas, and Conventional Insulin Pump Therapy for Glycaemic Cont. in Patients with Type 1 Diabetes: an Open-Label Rand Controlled Crossover Trial. Lancet Diabetes Endocrinol. 2014 Nov 26. 3(1):17-26 (Published).
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162. Del Favero, S., Bruttomesso, D., Cobelli, C. Artificial Pancreas: A Review of Fundamentals and Inpatient and Outpatient Studies. Frontiers in Diabetes 24:166-189 · January 2015 (Published).
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163. Stenerson M, Cameron F, Payne SR, Payne SL, Ly TT, Wilson DM, Buckingham BA. The impact of accelerometer use in exercise-associated hypoglycemia prevention in type 1 diabetes. J Diabetes Sci Technol. 2015 Jan;9(1):80-5 (Published).
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164. Brown S, Kovatchev B, Breton M, Anderson S, Keith-Hynes P, Patek S, Jiang Boyi, Brahim N, Vershchetin P, Bruttomesso D, Avogaro A, Favero S, Bosccari F, Galasso S, Visentin R, Monaro M, Cobelli C. Multinight ‘‘Bedside’’ Closed-Loop Control for Patients with Type 1 Diabetes. Diabetes Technology & Therapeutics. 2015 Mar. 17(3):203-209 (Published).
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165. Howsmon D, Bequette BW. Hypo- and Hyperglycemic Alarms: Devices and Algorithms. J Diabetes Sci Technol. 2015 Apr 30;9(5):1126-37 (Published).
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166. Zisser H, Dassau E, Lee JJ, Harvey RA, Bevier W, Doyle III FJ. Clinical results of an automated artificial pancreas using technosphere inhaled insulin to mimic first-phase insulin secretion. J Diabetes Sci Technol. 2015 May;9(3):564-72 (Published).
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167. Barnard KD, Pinsker JE, Oliver N, Astle A, Dassau E, Kerr D. Future Artificial Pancreas Technology for Type 1 Diabetes. What Do Users Want?. Diabetes Technology & Therapeutics. April 2015, 17(5): 311-315. doi:10.1089/dia.2014.0316. (Published).
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168. Barnard KD, Wysocki T, Thabit H, Evans ML, Amiel S, Heller S, Young A, Hovorka R; Angela Consortium.. Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting. Diabet Med. 2015 May;32(5):601-8 (Published).
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169. Del Favero S, Place J, Kropff J, Messori M, Keith-Hynes P, Visentin R, Monaro M, Galasso S, Boscari F, Toffanin C, Di Palma F, Lanzola G, Scarpellini S, Farret A, Kovatchev B, Avogaro A, Bruttomesso D, Magni L, DeVries JH, Cobelli C, Renard E. MC outpatient dinner/overnight reduction of hypoglycemia and increased time of glucose in target with a wearable artificial pancreas using modular model predictive control in adults w/ type 1 diabetes. Diabetes Obes Metab. 2015 May;17(5):468-76 (Published).
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170. Ruan Y, Thabit H, Leelarathna L, Hartnell S, Willinska ME, Dellweg S, Benesch C, Mader JK, Holzer M, Kojzar H, Evans ML, Pieber TR, Arnolds S, Hovorka R. Novel Communications in Diabetes - Variability of insulin requirements over 12-weeks of closed-loop insulin delivery in adults with type 1 diabetes. Diabetes Care 2016 May; 39(5): 830-832 (Published).
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171. Thabit H, Elleri D, Leelarathna L, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska ME, Barnard KD, Heller SR, Amiel SA, Evans ML, Dunger DB, Hovorka R. Unsupervised home use of overnight closed-loop system over 3 to 4 weeks – Pooled analysis of randomised controlled studies in adults and adolescents with type 1 diabetes. Diabetes Obesity and Metabolism 2015 May;17(5):452-8 (Published).
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172. Emami A, Rabasa-Lhoret R, Haidar A. Enhancing Glucose Sensor Models: Modeling the Drop-Outs. Diabetes Technology & Therapeutics. May 2015, 17(6): 420-426. doi:10.1089/dia.2014.0309. (Published).
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173. Wilson D, Calhoun P, Maahs D, Chase H, Messer L, Buckingham B, Aye T, Clinton P, Hramiak I, Kollman C, Beck R. Factors Associated with Nocturnal Hypoglycemia in At-Risk Adolescents and Young Adults with Type 1 Diabetes. Diabetes Technology & Therapeutics. 2015 Jun. 17(6):385-391 (Published).
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174. Buckingham BA, Raghinaru D, Cameron F, Bequette BW, Chase HP, Maahs DM, Slover R, Wadwa RP, Wilson DM, Ly T, Aye T, Hramiak I, Clarson C, Stein R, Gallego PH, Lum J, Sibayan J, Kollman C, Beck RW. Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis. Diabetes Care. 2015 Jul;38(7):1197-204 (Published).
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175. Haidar A, Legault L, Matteau-Pelletier L, Messier V, Dallaire M, Ladouceur M, Rabasa-Lhoret R. Outpatient Overnight Gluc Cont. w/ D-H Artificial Pancreas, S-H Artificial Pancreas, or Conventional Insulin Pump Therapy in Children and Adolescents w/ Type 1 Diabetes: an Open-Label, Rand Cont Trial. Lancet Diabetes Endocrinol. 2015 Aug. 3(8): 595-604 (Published).
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176. Ang K, Tamborlane WV, Weinzimer S. Combining glucose monitoring and insulin delivery into a single device: current progress and ongoing challenges of the artificial pancreas. Expert Opinion in Drug Delivery. 2015 Sept. 12 (10): 1579-1582 (Published).
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177. Diouri O, Place J, Traverso M, Georgescu V, Picot MC, Renard E. Development of a Smartphone Application to Capture Carbohydrate, Lipid, and Protein Contents of Daily Food: Need for Integration in Artificial Pancreas for Patients With Type 1 Diabetes?. J Diabetes Sci Technol. 2015 Sep 30;9(6):1170-4 (Published).
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178. Mauseth R, Lord SM, Hirsh IB, Kircher RC, Matheson DP, Greenbaum CJ. Stress Testing of an Artificial Pancreas System With Pizza and Exercise Leads to Improvements in the System's Fuzzy Logic Controller. Journal of Diabetes Science and Technology. 2015 Spet. 14;9 (6): 1253-1259 (Published).
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179. Kropff J, Favero S, PLace J, Toffanin C, Visentin R, Monaro M, Messori M, Palma F, Lanzola G, Farret A, Boscari F, Galasso S, Magni P, Avogaro A, Keith-Hynes P, Kovatchev B, Bruttomesso D, Cobelli C, DeVries J, Renard E, Magni L. 2 Month Evening and Night Closed-Loop Glucose Control in Patients with Type 1 Diabetes Under Free-Living Conditions: a Randomised Crossover Trial. Lancet Diabetes Endocrinol. 2015 Sept 30. 3(12): 939–947 (Published).
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180. Dassau E, Brown SA, Basu A, Pinsker JE, Kudva YC, Gondhalekar R, Patek S, Lv D, Schiavon M, Lee JB, Dalla Man C, Hinshaw L, Castorino K, Mallad A, Dadlani V, McCrady-Spitzer SK, McElwee-Malloy M, Wakeman CA, Bevier WC, Bradley PK, Kovatchev B, Cobelli C, Zisser HC, Doyle III FJ. Adjustment of Open-Loop Settings to Improve Closed-Loop Results in Type 1 Diabetes: A Multicenter Randomized Trial. J Clin Endocrinol Metab.2015; 100(10):3878-3886 (Published).
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181. DeSalvo DJ, Maahs DM, Messer L, Wadwa RP, Payne S, Ly TT, Buckingham BA. Effect of Lipohypertrophy on Accuracy of Continuous Glucose Monitoring in Patients With Type 1 Diabetes. Diabetes Care. 2015 Oct;38(10):e166-7 (Published).
(Manuscript) |  View Publication  
 
182. Maahs DM, DeSalvo D, Pyle L, Ly T, Messer L, Clinton P, Westfall E, Wadwa RP, Buckingham B. Effect of acetaminophen on CGM glucose in an outpatient setting. Diabetes Care. 2015 Oct;38(10):e158-9 (Published).
(Manuscript) |  View Publication  
 
183. Tauschmann M, Thabit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska ME, Heller SR, Amiel SA, Evans ML, Dunger DB, Hovorka R. Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes. J Diabetes Sci Technol. 2015 Oct 7;9(6):1346-7 (Published).
(Manuscript) |  View Publication  
 
184. Thabit H, Leelarathna L, Wilinska ME, Allen JM, Lubina-Solomon A, Walkinshaw E, Stadler M, Mader JK, Dellweg S, Benesch C, Pieber TR, Arnolds S, Heller SR, AMiel SA, Dunger D, Evans ML, Hovorka R. Accuracy of continuous glucose monitoring during three closed-loop home studies under free-living conditions. Diabetes Technology and Therapeutics. 2015 Jul;9(4):932-3 (Published).
(Manuscript) |  View Publication  
 
185. Cameron F, Fainekos G, Maahs DM, Sankaranarayanan S. Towards a Verified Artificial Pancreas: Challenges and Solutions for Runtime Verification. InRuntime Verification 2015 (pp. 3-17) (Published).
(Manuscript) |  View Publication  
 
186. Thabit H, Tauschmann M, Allen JM, Leelarathna L, Hartnell S, Willinska ME, Acerini CL, Dellweg S, Benesch C, Heinemann L, Mader JK, Holzer M, Kojzar H, Exall J, Yong J, Pichierri J, Barnard KD, Kollman C, Cheng P, Hindmarsh PC, Campbell FM, Arnolds S, Pieber TR, Evans ML, Dunger DB, Hovorka R. Free-living Home Use of an Artificial Beta Cell in Type 1 Diabetes. New England Journal of Medicine. Nov 2015; 373: 2129-2140 (Published).
(Manuscript) |  View Publication  
 
187. Tauschmann M, Allen J, Wilinska M, Thabit H, Stewart Z, Cheng P, Kollman C, Acerini C, Dunger D, Hovorka R. Day-and-Night Hybrid Closed-Loop Insulin Delivery in Adolescents With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial. Diabetes Care. 2016 Jan. DOI: 10.2337/dc15-2078 (Published).
(Manuscript) |  View Publication  
 
188. Gingras V, Rabasa-Lhoret R, Messier V, Ladouceur M, Legault L, Haidar A. Efficacy of Dual-Hormone Artificial Pancreas to Alleviate the Carbohydrate Counting Burden in Type 1 Diabetes: Randomized Crossover Trial. Diabetes and Metabolism. 2016 Feb. 42(1): 47-54 (Published).
(Manuscript) |  View Publication  
 
189. Kropff J, DeVries JH. Continuous Glucose Monitoring, Future Products, and Update on Worldwide Artificial Pancreas Projects. Diabetes Technology & Therapeutics. January 2016, 18(S2): S2-53-S2-63. doi:10.1089/dia.2015.0345. (Published).
(Manuscript) |  View Publication  
 
190. Messer LH, Calhoun P, Buckingham B, Wilson DM, Hramiak I, Ly TT, Driscoll M, Clinton P, Maahs DM. In-home nighttime predictive low glucose suspend experience in children and adults with type 1 diabetes. Pediatr Diabetes. 2016 Apr 29. doi: 10.1111/pedi.12395 (Published).
(Manuscript) |  View Publication  
 
191. Gonder-Frederick L, Grabman JH, Kovatchev B, Brown SA, Patek D, Basu A, Pinsker JE, Kudva YC, Wakeman CA, Dassau E, Cobelli C, Zisser HC, Doyle III FJ. Is Psychological Stress a Factor for Incorporation in Future Closed-Systems?. Journal of Diabetes Science and Technology. 2016 May; 10(3): 640-646 (Published).
(Manuscript) |  View Publication  
 
192. Jacobs PG, El Youssef J, Castle J, Bakhtiani P, Branigan D, Breen M, Bauer D, Preiser N, Leonard G, Stonex T, Ward WK.. Automated Control of an Adaptive Bi-hormonal, Dual-Sensor Artificial Pancreas and Evaluation During Inpatient Studies. IEEE Trans Biomed Eng. 2014 Oct;61(10):2569-81. doi: 10.1109/TBME.2014.2323248 (Published).
(Manuscript) |  View Publication  
 
193. Heinemann L, Benesch C, DeVries JH. AP@home: The Artificial Pancreas Is Now at Home. J Diabetes Sci Technol. 2016 Jun 28;10(4):950-8 (Published).
(Manuscript) |  View Publication  
 
194. Anderson SM, Raghinaru D, Pinsker JE, Boscari F, Renard E, Buckingham BA, Nimri R, Doyle III FJ, Brown SA, Keith-Hynes P, Breton MD, Chernavvsky D, Bevier WC, Bradley PK, Bruttomesso D, Del Favero S, Calore R, Cobelli C, Avogaro A, Farret A, Place J, Ly TT, Shanmugham S, Phillip M, Dassau E, Dasanayake IS, Kollman C, Lum JW, Beck RW, Kovatchev B. Multinational Home Use of Closed-loop Control is Safe and Effective. Diabetes Care. 2016 Jul;39(7):1143-50 (Published).
(Manuscript) |  View Publication  
 
195. Blauw H, van Bon AC, Koops R, DeVries JH. Performance and safety of an integrated bihormonal artificial pancreas for fully automated glucose control at home. Diabetes Obes Metab. 2016 Jul;18(7):671-7 (Published).
(Manuscript) |  View Publication  
 
196. Del Favero S, Boscari F, Messori M, Rabbone I, Bonfanti R, Sabbion A, Iafusco D, Schiaffini R, Visentin R, Calore R, Leal Moncada Y, Galasso S, Galderisi A, Vallone V, Di Palma F, Losiouk E, Lanzola G, Tinti D, Rigamonti A, Marigliano M, Zanfardino A, Rapini N, Avogaro A, Chernavvsky D, Magni L, Cobelli C, Bruttomesso D. Randomized Summer Camp Crossover Trial in 5- to 9-Year-Old Children: Outpatient Wearable Artificial Pancreas Is Feasible and Safe. Diabetes Care. 2016 Jul;39(7):1180-5 (Published).
(Manuscript) |  View Publication  
 
197. Pinsker JE, Lee JB, Dassau E, Seborg DE, Bradley PK, Gondhalekar R, Bevier WC, Huyett L, Zisser HC, Doyle III FJ. Randomized Crossover Comparison of Personalized MPC and PID Control Algorithms for the Artificial Pancreas. Diabetes Care. 2016; DOI: 10.2337/dc15-2344 (Published).
(Manuscript) |  View Publication  
 
198. Renard E, Farret A, Kropff J, Bruttomesso D, Messori M, Place J, Visentin R, Calore R, Toffanin C, Di Palma F, Lanzola G, Magni P, Boscari F, Galasso S, Avogaro A, Keith-Hynes P, Kovatchev B, Del Favero S, Cobelli C, Magni L, DeVries JH. Day/Night CL Glucose Cont. in Pts W/ Type 1 Diabetes Under FreeLiving Conditions: Results of a Single-Arm 1-Month Experience Comp. W/ a Previously Rprtd Feasibility Study of Evening and Night at Home. Diabetes Care. 2016 Jul;39(7):1151-60 (Published).
(Manuscript) |  View Publication  
 
199. Anderson S, Cherñavvsky DR, Kovatchev BP, Cobelli C, Renard E, Farret A, Buckingham BA, Ly TT, Pinsker J, Doyle III FJ, Nimri R, Beck RW. First New Year's Night on Closed-Loop Control (CLC) at Home: Case Reports from a Multicenter International Trial of Long-Term 24/7 CLC. Presented at the American Diabetes Association, Boston, MA, June 2015 (Published).
(Manuscript)  
 
200. Castle J, Engle J, El Youssef J, Massoud RG, Yuen KCJ, Kagan R, Ward WK. Novel Use of Glucagon in a Closed-Loop System for Prevention of Hypoglycemia in Type 1 Diabetes. Diabetes Care. 2010 Jun;33(6):1282-7 (Published).
(Manuscript) |  View Publication  
 
201. Castle JR, Engle J, El Youssef J, Massoud RG, Ward WK. Predictors of Glucagon Success vs Failure in Preventing Hypoglycemia during Closed-loop Treatment of Type 1 Diabetes. J Diabetes Sci Tech 2010; 4:1305-10 (Published).
(Manuscript)  
 
202. Castle JR, Pitts A, Hanavan K, Muhly R, El Youssef J, Karvetski C, Kovatchev B, Ward WK. Accuracy benefit of multiple amperometric glucose sensors in persons with type 1 diabetes. Diabetes Care. 2012 Apr;35(4):706-10 (Published).
(Manuscript) |  View Publication  
 
203. Castle, J.R., Pitts, K., Hanavan, K., Muhly, R., Youssef, J.El., Karvetski, C.h., Kovatechev, B., Ward, K.W.,. The Accuracy Benefit of Multiple Amperometric Glucose Sensors in Persons with Type 1 Diabetes. Diabetes Care. 2012 Apr;35(4):706-10 (Published).
(Manuscript) |  View Publication  
 
204. El Youssef, J, Castle JR, Ward WK. A Review of Closed-Loop Algorithms for Glycemic Control in the Treatment of Type 1 Diabetes. Algorithms 2:518-32, 2009 (Published).
(Manuscript) |  View Publication  
 
205. El Youssef, J., Castle, J.R., Branigan, D.L., Massoud, R.G., Breen, M.E., Jacobs, P.G., Bequette, B.W., and Ward W.K. A controlled study of the effectiveness of an adaptive closed-loop algorithm to minimize corticosteroid-induced stress hyperglycemia in type 1 diabetes. J Diabetes Sci Technol. 2011 Nov 1;5(6):1312-26 (Published).
(Manuscript) |  View Publication  
 
206. Jacobs PG, El Youssef J, Castle JR, Engle JM, Branigan DL, Johnson P, Massoud R, Kamath A, Ward WK. Development of a fully automated closed loop artificial pancreas control system with dual pump delivery of insulin and glucagon. Conf Proc IEEE Eng Med Biol Soc.2011:397-400 (Published).
(Manuscript) |  View Publication  
 
207. Ly TT, Nicholas JA, Retterath A, Davis EA, Jones TW. Analysis of glucose responses to automated insulin suspension with sensor-augmented pump therapy. Diabetes Care July 2012 35:1462-1465 (Published).
(Manuscript) |  View Publication  
 
208. Ruiz JL, Sherr JL, Cengiz E, Carria L, Roy A, Voskanyan G, Tamborlane WV, Weinzimer SA. Effect of insulin feedback on closed-loop glucose control: a crossover feedback study. J Diabetes Sci Technol. 2012 Sep 1;6(5):1123-30 (Published).
(Manuscript) |  View Publication  
 
209. Russell S, El-Khatib F, Sinha M, Magyar K, McKeon K, Goergen L, Balliro C, Hillard M, Nathan D, Damiano E. Outpatient Glycemic Control with a Bionic Pancreas in Type 1 Diabetes. N Engl J Med. 2014 Jul 24;371(4):313-25. doi: 10.1056/NEJMoa1314474. Epub 2014 Jun 15. (Published).
(Manuscript) |  View Publication  
 
210. Ward WK. Continuous Glucose Monitoring in the Intensive Care Unit (commentary). Journal Diabetes Sci Tech 6:1372-1374 2012 (Published).
(Manuscript)  
 
211. Ward WK, Van Albert S, Bodo M, Pearce F, Gray R, Harlson S. Design and Assessment of a Miniaturized Amperometric Oxygen Sensor in Rats and Pigs. IEEE Sensors Journal ( Volume: 10, Issue: 7, July 2010 ) (Published).
(Manuscript) |  View Publication  
 
212. Ward, W.K., Castle, J.R., and El Youssef, J. Safe glycemic management during closed-loop treatment of type 1 diabetes: the role of glucagon, use of multiple sensors, and compensation for stress hyperglycemia. J Diabetes Sci Technol. 2011 Nov 1;5(6):1373-80 (Published).
(Manuscript) |  View Publication  
 
213. Ward, WK, Castle JR, Branigan DL, Massoud RG, El Youssef J. Discomfort from an Alkaline Formulation Delivered Subcutaneously in Humans: Albumin at pH 7 versus pH 10. Clin Drug Investig. 2012 Jul 1;32(7):433-8 (Published).
(Manuscript) |  View Publication  
 

Protocol PumpOff01 - Prevention of Nocturnal Hypoglycemia using predictive algorithms and pump shut-off.

1. Buckingham BA., Cameron F., Calhoun P., Maahs DM., Wilson DM., Chase HP., Bequette BW., Lum J., Sibayan J., Beck RW., Kollman C.. Outpatient Safety Assessment of an In-Home Predictive Low-Glucose Suspend System with Type 1 Diabetes Subjects at Elevated Risk of Nocturnal Hypoglycemia. Diabetes Technol Ther. 2013 Aug;15(8):622-7 (Published).
(Manuscript) |  View Publication  
 

Meeting Abstracts

General

1. Weinzimer SA, Steil GM, Kurtz N, Swan KL, Tamborlane WV. Automated Feedback-Controlled Insulin Delivery in Children with Type 1 Diabetes (T1D): A Preliminary Report. 66th Scientific Sessions of the American Diabetes Association, Washington, DC, Jun 9-13, 2006 (Published).
(Poster)  
 
2. Weinzimer SA, Steil GM, Kurtz N, Swan KL, Tamborlane WV. Closed-Loop Artificial Pancreas: Feasibility Studies in Pediatric Patients with Type 1 Diabetes (T1D). Sixth Annual Diabetes Technology Meeting, Atlanta, GA, Nov 2-4, 2006 (Published).
(Oral Presentation)  
 
3. Weinzimer SA, Steil GM, Kurtz N, Swan KL, Tamborlane WV. Comparison of Prandial Insulin Delivery During Closed-Loop Control with Standard Insulin Pump Therapy Bolus Insulin Delivery. Sixth Annual Diabetes Technology Meeting, Atlanta, GA, Nov 2-4, 2006 (Published).
(Poster)  
 
4. El-Khatib FH, Jiang J, Damiano ER. Optimized, self-learning, in vivo blood-glucose control using dual subcutaneous infusion in a type 1 diabetic swine model. 66th Scientific Sessions of the American Diabetes Association, Washington, DC, Jun 9-13, 2006 (Published).
(Oral Presentation)  
 
5. El-Khatib FH, Jiang J, Damiano ER. Adaptive closed-loop control provides robust blood-glucose regulation using dual subcutaneous insulin and glucagon infusion in ambulatory diabetic swine. 67th Scientific Sessions of the American Diabetes Association, Chicago, IL, Jun 22-26, 2007 (Published).
(Oral Presentation)  
 
6. El-Khatib FH, Jiang J, Damiano ER. Closed-loop blood-glucose control using dual subcutaneous insulin and glucagon infusion in vivo. Proceedings of the 2006 BMES Annual Fall Meeting, Chicago, IL, Oct 11-14, 2006 (Published).
(Oral Presentation)  
 
7. Cameron F, Chase P, Buckingham B, Niemeyer G. Statistical Linear Prediction Using Continuous Glucose Measurements for the Predictive Detection of Hypoglycemia. Seventh Annual Diabetes Technology Meeting, San Francisco, CA, Oct 25-27, 2007 (Published).
(Oral Presentation)  
 
8. Dassau E, Bequette BW, Palerm CC, Buckingham B, Gandrud L, Doyle FJ. Detection of a Meal Using Continuous Glucose Monitoring (CGM), Implications for Model Predictive Control Using Real-TIme CGM. Diabetes 56:A23, 2007 (Published).
(Oral Presentation)  
 
9. Dassau E, Palerm CC, Taub MB, Rebrin K, Buckingham BA, Doyle FJ. In Silico Dynamic Simulator for Closed-Loop Control of an Artificial B-Cell with Hardware-in-the-Loop. Seventh Annual Diabetes Technology Meeting, San Francisco, CA, Oct 25-27, 2007 (Published).
(Oral Presentation)  
 
10. Finan DA, Bevier WC, Zisser H, Jovanovic L, Seborg DE. Monitoring and Empirical Modeling Strategies for Type 1 Diabetes Patients. J Diabetes Sci Technol 1:A34, 2007 (Published).
(Oral Presentation)  
 
11. Finan DA, Palerm CC, Zisser H, Bevier WC, Jovanovic L, Doyle FJ, Seborg DE. Pre-Filtering the Insulin Input Improves the Quality of Empirical Models Identified from Clinical Type 1 Diabetes Data. AlChE Annual Meeting, Salt Lake City UT, November 2007 (Published).
(Oral Presentation)  
 
12. Finan DA, Percical MW, Palerm CC, Bevier WC, Zisser H, Jovanovic L, Doyle FJ, Seborg DE. A Comparison of Physiological and Empirical Models for Type 1 Diabetes Identified from Clinical Data. J Diabetes Sci Technol 1:A41, 2007 (Published).
(Oral Presentation)  
 
13. Gillis R, Palerm CC, Zisser H, Bevier WC, Jovanovic L, Seborg DE, Doyle FJ. Real-Time Glucose Prediction Using Mathematical Models and Subject Data. Diabetes 56:A110, 2007 (Published).
(Oral Presentation)  
 
14. Hovorka R, Wilinska ME, Chassin LJ, Allen J, Acerini CL, Dunger DB. Closing the Loop: Cambridge Ingredients for an Old Recipe. Seventh Annual Diabetes Technology Meeting, San Francisco, CA, Oct 25-27, 2007 (Published).
(Oral Presentation)  
 
15. Lee H, Dassau E, Doyle FJ, Buckingham BA, Bequette BW. Meal Detection and Magnitude Estimation Based on Glucose Monitoring. Seventh Annual Diabetes Technology Meeting, San Francisco, CA, Oct 25-27, 2007 (Published).
(Oral Presentation)  
 
16. Marchetti G, Barolo M, Zisser H, Jovanovic L, Seborg D. Preprandial and Feedforward-Feedback Control Strategies Can Improve Postprandial Responses for Type 1 Diabetes. J Diabetes Sci Technol 1:A107, 2007 (Published).
(Oral Presentation)  
 
17. Wilinska ME, Chassin LJ, Hovorka R. Artificial Pancreas: Getting There Faster. 26th AIDPIT Meeting, Montpellier, France, 2007 (Published).
(Oral Presentation)  
 
18. Wilinska ME, Chassin LJ, Hovorka R. The Role of Simulation Environment in the Development of Artificial Pancreas for Overnight Glucose Control in Children and Adolescents with Type 1 Diabetes. Seventh Annual Diabetes Technology Meeting, San Francisco, CA, Oct 25-27, 2007 (Published).
(Oral Presentation)  
 
19. Cameron F, Niemeyer G, Palerm CC, Dassay E, Doyle FJ,Lee H, Bequette BW, Chase HP, Buckingham B. Early Detection of Hypoglycemia Combining Multiple Predictive Methods on Retrospective Clinical Continuous Glucose Monitoring Data. J Diabetes Sci Technol 2:A19, 2007 (Published).
(Oral Presentation)  
 
20. Percival MW, Palerm CC, Bevier WC, Zisser H, Jovanovic L, Seborg DE, Doyle FJ. State Estimation Methods for Prediction of Glycemia in Type 1 Diabetes Mellitus. AlChE Annual Meeting, Salt Lake City UT, November 2007 (Published).
(Oral Presentation)  
 
21. Breton MD, Anderson S, Kovatchev B. Analysis, Modeling, and Simulation of the Accuracy of Continuous Glucose Sensors. AIDPIT 2008, Innsbruck-Igls, Austria (Published).
(Oral Presentation)  
 
22. Buckingham BA, Wilson DM, Doyle FJ, Dassau E, Bequette BW, Lee H, Chase HP, Cobry EC. The JDRF Artificial Pancreas (AP) Project, The Consortium of Stanford, UCSB, Rensselaer Institute and the Barbara Davis Center. 1st Conference on Advanced Technologies and Treatments for Diabetes, Prague, Czech Republic, 2008 (Published).
(Oral Presentation)  
 
23. Cameron F, Niemeyer G, Gundy-Berlet K, Buckingham BA. Locally Weighted Learning Improves Sensor Glucose (SG) Prediction Accuracy. 68th Scientific Sessions of the American Diabetes Association, San Francisco, CA, Jun 6-10, 2008 (Published).
(Oral Presentation)  
 
24. Dassau E, Herrero P, Zisser H, Buckingham BA, Jovanovic L, Dalla Man C, Vehi J, Doyle FJ. Implications of Meal Library and Meal Detection to Glycemic Control of Type 1 Diabetes Mellitus Through MPC Control. IFAC World Congress 2008, Seoul, Korea (Published).
(Oral Presentation)  
 
25. Dassau E, Palerm CC, Taub MB, Rebrin K, Campbell RW, Buckingham BA, Doyle FJ. In-Silico Benchmark Platform for Artificial B-Cell- A Dynamic Simulator for Closed-Loop Control with Hardware In-The-Loop. AIDPIT, Innsbruck, Austria, 2008 (Published).
(Oral Presentation)  
 
26. Dassau E, Palerm CC, Zisser H, Buckingham B, Jovanovic L, Doyle FJ. Software & Hardware Implementation of an Artificial B-Cell: Modular Prototype Development and Risk Management. J Diabetes Sci Technol 2:A28, 2008 (Published).
(Oral Presentation)  
 
27. Dassau E, Zisser H, Buckingham BA, Jovanovic L, Doyle FJ. Closing the Loop Artificial Pancreas (B-Cell) - Engineering Perspective. 1st Conference on Advanced Technologies and Treatments for Diabetes, Prague, Czech Republic, 2008 (Published).
(Oral Presentation)  
 
28. Finan DA, Palerm CC, Doyle FJ, SEborg DE, Bevier WC, Zisser H, Jovanovic L. Detection of Pharmacologically Induced Stress in Subjects with Type 1 Diabetes. J Diabetes Sci Technol 2:A42, 2008 (Published).
(Oral Presentation)  
 
29. Herreero P, Palerm CC, Dassau E, Zisser H, Jovanovic L, Dalla Man C, Cobelli C, Vehi J, Doyle FJ. A Glucose Absorption Model Library of Mixed Meals for In-Silico Evaluation of Artificial B-Cell Control Algorithms. J Diabetes Sci Technol 2:A70, 2008 (Published).
(Oral Presentation)  
 
30. Hovorka R, Acerini CL, Allen J, Chassin LJ, Larsen AF, Mundt D, De Palma A, Wilinska ME, Dunger DB. Good overnight closed-loop glucose control in children and adolescents with type 1 diabetes following ingestion of large, rapidly and slowly absorbed evening meat. Diabetologia 51:181, 2008 (Published).
(Meeting Abstract)  
 
31. Larsen AM, Acerini C, Allen J, Chassin LJ, Wilinska ME, Dunger D, Hovorka R. Accuracy and Performance of CGMs and Guardian RT in Children and Adolescents with Type 1 Diabetes. AIDPIT 2008, Innsbruck-Igls, Austria (Published).
(Oral Presentation)  
 
32. Lee H, Caswell K, Dassau E, Doyle FJ, Buckingham BA, Bequette BW. A Clinical Study of Meal Size Estimation Analysis Using Continuous Glucose Monitoring (CGM) Data. 68th Scientific Sessions of the American Diabetes Association, San Francisco, CA, Jun 6-10, 2008 (Published).
(Oral Presentation)  
 
33. Lee H, Palerm CC, Bevier W, Zisser H, Jovanovic L, Buckingham B, Doyle FJ, Bequette BW. Time-Varying Insulin Sensitivity in an In-Silico Model of Subjects with Type 1 Diabetes. J Diabetes Sci Technol 2:A96, 2008 (Published).
(Oral Presentation)  
 
34. Ward WK, J Engle, HM Duman, CP Bergstrom, et al. The Benefit of Subcutaneous Glucagon During Closed-Loop Glycemic Control in Rats With Type 1 Diabetes. IEEE Sensors 8:89-96, 2008 (Published).
(Oral Presentation)  
 
35. Ward WK, Li AG, Siddiqui Y, Federiuk IF, Wang XJ. Increased Expression of Interleukin-13 and Connective Tissue Growth Factor, and their Potential Roles during Foreign Body Encapsulation of Subcutaneous Implants. Journal of Biomaterials Science, Polymer Edition 19:1065-1072, 2008 (Published).
(Oral Presentation)  
 
36. Zisser H, Palerm CC, Finan DA, Dassau E, Gillis RS, Percival MW, Bevier WC, Jovanovic L, Seborg DE, Doyle FJ. Clinical Insights from preliminary Testing of an Artificial B-Cell Control Algorithm-Modeling and Tuning. J Diabetes Sci Technol 2:A187, 2008 (Published).
(Oral Presentation)  
 
37. Hovorka T, Wilinska ME, Schaller HC, Pieber TR, Schaupp L, Hovorka R. Estimating process noise of glucose excursions in type 1 diabetes. J Diabetes Sci Technol 2:A73, 2008. (Published).
(Meeting Abstract)  
 
38. Hovorka R, Acerini CL, Allen J, Chassin LJ, Larsen AM, De Palma A, Wilinska ME, Dunger DB,. Overnight sc-sc Closed-Loop Control Improves Glucose Control and Reduces Risk of Hypoglycemia in Children and Adolescents with Type 1 Diabetes. 68th Scientific Sessions of the American Diabetes Association, San Francisco, CA, Jun 6-10, 2008 (Published).
(Oral Presentation)  
 
39. Percival MW, Lee H, Bequette BW, Zisser H, Jovanovic L, Doyle FJ. Real-Time Estimate of the Circadian Variation in Insulin Sensitivity in a Virtual Subject. 68th Scientific Sessions of the American Diabetes Association, San Francisco, CA, Jun 6-10, 2008 (Published).
(Oral Presentation)  
 
40. Zisser H, Dassau E, Bevier WC, Jovanovic L, Doyle FJ. Basal Insulin-On-Board Constraint in the Implementation of Closed-Loop Control. 68th Scientific Sessions of the American Diabetes Association, San Francisco, CA, Jun 6-10, 2008 (Published).
(Oral Presentation)  
 
41. Zisser H, Dassau E, Paband R, Bevier WC, Wollitzer AO, Jovanovic L. Distribution of Glucose Concentrations Using a Seven-Day Continuous Glucose Sensor in Subjects Without Diabetes. 68th Scientific Sessions of the American Diabetes Association, San Francisco, CA, Jun 6-10, 2008 (Published).
(Oral Presentation)  
 
42. Finan DA, Palerm CC, Doyle III FJ, Zisser H, Jovanovic L, Bevier WC, Seborg DE. Identification of Empirical Dynamic Models from Type 1 Diabetes Subject Data. 2008 American Control Conference Seattle, WA ,June 11-13 2008 (Published).
(Oral Presentation)  
 
43. Percival MW, Bevier WC, Zisser H, Jovanovic L, Seborg DE, Doyle FJ. Prediction of Dynamic Glycemic Trends Using Optimal State Estimation. IFAC World Congress, Seoul, Korea July 2008 (Published).
(Oral Presentation)  
 
44. Gani A, Gribok AV, Rajaraman S, Ward WK, Reifman J. Predicting subcutaneous glucose concentration in humans: data-driven glucose modeling. IEEE Trans Biomed Eng 56:246-254, 2009 (Published).
(Oral Presentation)  
 
45. El-Khatib FH, Jiang J, Nathan DM, Russell SJ, Damiano ER. Closed-loop blood-glucose control using dual subcutaneous infusion of insulin and glucagon in ambulatory diabetic pigs. Eighth Annual Diabetes Technology Meeting, Bethesda, MD, Nov 13-15, 2008 (Published).
(Oral Presentation)  
 
46. Allen JM, Elleri D, Acerini CL, Larsen AM, Mangat JS, De Palma A, Wilinska ME, Dunger DB, Hovorka R. Artificial pancreas project at Cambridge: Year 2 status and toward home testing. J Diabetes Sci Technol 3:A4, 2009 (Published).
(Meeting Abstract)  
 
47. Elleri D, Acerini CL, Allen JM, Chassin LJ, Kollman C, Harris, Hovorka T, Larsen AM, Nodale M, De Palma A, Wilinska ME, Xing DY, Dunger DB, Hovorka R. Overnight closed-loop (CL) glucose control in children and adolescents with type 1 diabetes (T1D): towards home testing. Hormone Research 72:32-32, 2009 (Published).
(Meeting Abstract)  
 
48. Elleri D, Acerini CL, Allen JM, Hayes JF, Larsen AM, Pesterfield C, Wilinska ME, Dunger DB, Hovorka R. Parental attitudes toward the artificial pancreas for overnight glucose control in type 1 diabetes. Diabetes Technol Ther. 2010 Jan;12(1):35-9 (Published).
(Meeting Abstract) |  View Publication  
 
49. Finan DA, Bevier WC, Zisser H, Jovanovic L, Seborg DE. Multivariate statistical monitoring strategy for an artificial pancreas application. Presented at the Nordick Process Control Workshop, Norway, 2009 (Published).
(Oral Presentation)  
 
50. Hovorka R, Acerini CL, Allen JM, Chassin LJ, Kollman C, Elleri D, Harris J, Hovorka T, Larsen AMF, Nodale M, De Palma A, Wilinska ME, Xing D, Dunger DB. Overnight closed-loop insulin delivery in children and adolescents with type 1 diabetes: Towards home testing.. Diabetes 58:A54, 2009 (Published).
(Meeting Abstract)  
 
51. Larsen AM, Acerini CL, Allen JM, Chassin LJ, De Palma A, Wilinska ME, Dunger DB, Hovorka R. Evaluation of FreeStyle Navigator in children and adolescents with type 1 diabetes. J Diabetes Sci Technol 3:A96, 2009 (Published).
(Meeting Abstract)  
 
52. Steil GM, Deiss D, Shih J, Buckingham BA, Weinzimer S, Agus MS. Intensive Care Unit Insulin Delivery Algorithms: Why So Many? How to Choose?. J Diabetes Sci Technol 3:125-140, 2009 (Published).
(Oral Presentation)  
 
53. Ward WK and Duman HM. Strategies to Overcome Biological Barriers to Biosensing in Biosensors. State of the Art and Challenges, J. Stenken, Editor. 2009, Wiley: In press (Published).
(Oral Presentation)  
 
54. Bondia J, Dassau E, Zisser H, Calm R, Vehi J, Jovanovic L, Doyle III FJ. Role of basal insulin in postprandial glucose control with pump therapy. Presented at the 2nd Conference of Advanced Technologies & Treatments for Diabetes, Athens, Greece, 2009 (Published).
(Poster)  
 
55. Dassau E, Campos-Delgado D, Campos-Cornejo F, Espinoza-Trejo D, Zisser H, Jovanovic L, Doyle III FJ. Dual insulin therapy- Robustness evaluation of a run-to-run control strategy. Presented at the 2nd conference on Advanced Technologies & Treatments for Diabetes, Athens, Greece, 2009 (Published).
(Poster)  
 
56. Wang Y, Dassau E, Zisser H, Jovanovic L, Doyle III FJ. Learning-type model predictive control (L-MPC) in artificial pancreatic ß-cell. Presented at the 2nd International Conference on Advanced Technologies & Treatments for Diabetes, Athens, Greece, 2009 (Published).
(Oral Presentation)  
 
57. Zisser H, Bevier W, Dassau E, Jovanovic L. The Siphon Study: Hydrostatic effects on insulin pump delivery performance. Presented at the 2nd Conference on Advanced Technologies & Treatments for Diabetes, Athens, Greece, 2009 (Published).
(Poster)  
 
58. Wilinska ME, Acerini CL, Allen JM, Chassin LJ, Dunger DB, Hovorka R. Validation of simulation environment utilizing clinical data collected during overnight closed-loop glucose control in children and adolescents with type 1 diabetes. J Diabetes Sci Technol 3:A175, 2009 (Published).
(Meeting Abstract)  
 
59. El-Youssef J, Castle J, Ward WK. A Review of Closed-Loop Algorithms for Glycemic Control in the Treatment of Type 1 Diabetes. Algorithms 2:518-532, 2009 (Published).
(Oral Presentation)  
 
60. Dassau E, Zisser H, Grosman B, Bevier W, Percival MW, Jovanovic L, Doyle III FJ. Artificial pancreatic ß-cell protocol for enhanced model identification. Diabetes 2009: 58 (Suppl 1); A105 (Published).
(Poster)  
 
61. Dassau E, Zisser H, Jovanovic L, Doyle III FJ. Enhanced 911/GPS wizard for the prevention of severe hypoglycemia: Monitor, alerts and locate. Diabetes 2009: 58 (Suppl 1); A506 (Published).
(Poster)  
 
62. Percival MW, Bevier WC, Wang Y, Dassau E, Zisser H, Jovanovic L, Doyle FJ III. Development of a minimal model of carbohydrate and subcutaneous insulin effects on glycemia. Presented at American Diabetes Association meeting, 2009 (Published).
(Poster)  
 
63. Percival MW, Grosman B, Dassau E, Zisser H, Jovanovic L, Doyle III FJ. Automated insulin delivery system demonstrates safe and efficacious control of glycemia. Presented at the American Diabetes Association meeting, 2009 (Published).
(Poster)  
 
64. Wang Y, Mauseth RS, Kircher Jr RC, Mathson DP, Dassau E, Zisser H, Jovanovic L, Doyle III FJ. In silico evaluation of fuzzy logic controller for artificial pancreatic ß-cell. Presented at the American Diabetes Association meeting, 2009 (Published).
(Poster)  
 
65. Wang Y and Doyle III FJ. Indirect iterative learning control: application on artificial pancreatic ß cell. Proceedings of CCDC, 2009 (Published).
(Oral Presentation)  
 
66. Dassau E, Grosman B, Wang Y, Percival W, Zisser H, JOvanovic L, Seborg DE, Doyle III FJ. UCSB/Sansum steps toward artificial pancreatic ß-cell. Presented at the Diabetes Technology meeting, San Francisco, CA, 2009 (Published).
(Poster)  
 
67. Dassau E, Zisser H, Percival MW, Grosman B, Atlas E, Nimri R, Phillip M, Jovanovic, Doyle FJ III. The use of telemedicine in the development of artificial pancreatic ß-cell. Presented at the Diabetes Technology meeting, San Francisco, CA, 2009 (Published).
(Poster)  
 
68. Grosman B, Dassau E, Doyle FJ. Identifying dynamic of glycemia by genetic programming. Presented at the Diabetes Technology meeting, San Francisco, CA, 2009 (Published).
(Poster)  
 
69. Grosman B, Percival MW, Dassau E, Finan DA, Zisser H, Jovanovic L, Seborg DE, Forgione M, Magni L, De Nicolao G, Cobelli C, Doyle FJ III. Automated modeling approach for closed-loop control of an artificial pancreatic ß-cell. Presented at the Diabetes Technology meeting, San Francisco, CA, 2009 (Published).
(Poster)  
 
70. Kovatchev B, Patek S, Breton M, Zisser H, Jovanovic L, Doyle FJ III. Safety supervision module in open- and closed-loop control of diabetes. Presented at the Diabetes Technology meeting, San Francisco, CA, 2009 (Published).
(Poster)  
 
71. Wang Y, Mauseth RS, Kircher Jr RC, Zisser H, Jovanovic L, Dassau E, Matheson DP, Doyle III FJ. Use of personalization of fuzzy loci controller (FLC) for physician decision-making based on extremes in meal sizes using in silico testing. Presented at the Diabetes Technology meeting, San Francisco, CA, 2009 (Published).
(Poster)  
 
72. Wang Y, Zisser H, Bevier WC, Dassau E, Percival MW, Jovanovic L, Doyle III FJ. Clinical and in silico evaluation of adaptive basal therapy. Presented at the Diabetes Technology meeting, San Francisco, CA, 2009 (Published).
(Poster)  
 
73. Wang Y, Percival MW, Zisser H, Jovanovic L, Doyle III FJ. Automatic insulin delivery for type 1 diabetes mellitus using offline learning-type model predictive control (L-MPC). Presented at the AlChE Annual meeting, 2009 (Published).
(Oral Presentation)  
 
74. Dassau E, Atlas E, Phillip M. Diabetes Yearbook: Closing the loop. Presented at the 3rd Conference on Advanced Technologies & Treatments for Diabetes, Basel, Switzerland, 2010 (Published).
(Oral Presentation)  
 
75. Dassau E, Zisser H, Percival MW, Grosman B, Jovanovic L, Doyle III FJ. Clinical results of automated artificial pancreatic ß-cell system with unannounced meal using pancreatic multiparametric MPC and insulin-on-board. Diabetes 2010; 59 (Suppl 1): A94 (Published).
(Oral Presentation)  
 
76. Grosman B, Dassau E, Zisser H, Jovanovic L, Doyle III FJ. Automatic zone model predictive control for the artificial pancreatic ß-cell. Diabetes 2010; 59 (Suppl 1): A144 (Published).
(Poster)  
 
77. Kircher R, Wang Y, Dassau E, Zisser H, Jovanovic L, Doyle III FJ, Matheson D, Mauseth R. Reducing postprandial hypoglycemia using fuzzy logic controller with insulin dosing governor. Diabetes 2010; 59 (Suppl 1): A95 (Published).
(Poster)  
 
78. Elleri D, Harris J, Kumareswaran K, Allen JM, Haidar A, Nodale M, Swamy A, Wilinska ME, Weston J, Acerini CL, Jackson N, Umpleby AM, Evans ML, Dunger DB, Hovorka R. Glucose appearance of large slowly-absorbed evening meal containing complex carbohydrates (CHO) in type 1 diabetes (T1D). Diabetologia 53:S272, 2010 (Published).
(Meeting Abstract)  
 
79. Haidar A, Elleri D, Allen JM, Harris J, Kumareswaran K, Nodale M, Acerini CL, Wilinska ME, Jackson N, Umpleby AM, Evans ML, Dunger DB, Hovorka R. Tripple tracer (TT) and double tracer (DT) techniques are reliable methods to estimate glucose appearance in type 1 diabetes. Diabetologia 53:S271, 2010 (Published).
(Meeting Abstract)  
 
80. Kumareswaran K, Harris J, Elleri D, Allen JM, Nodale M, Wilinska ME, Dunger DB, Amiel SA, Heller SR, Evans ML, Hovorka R. Overnight closed-loop glucose control following consumption of alcohol in adults with type 1 diabetes. Diabetologia 52:S25, 2010 (Published).
(Meeting Abstract) |  View Publication  
 
81. Bequette BW, Lee H, Sun J, El Youssef J, Castle JR, Ward WK. A model of glucagon-glucose dynamics for closed-loop glycemic control. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
82. Bevier W, Zisser H, Jovanovic L. Continuous glucose monitoring: Exercise training level and differences in glucose variability. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
83. Bevier W, Zisser H, Jovanovic L. Tale of two women: Continuous glucose monitoring and exercise. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
84. Breton MD, Farret A, Place J, Hughes C, Patek SD, Cobelli C, Doyle III FJ, Kovatchev B, Renard E. Safety supervision system: First clinical trials. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
85. Cameron F, Niemeyer G, Buckingham BA, Lee H, Bequette W, Wilson DM. Improving closed-loop control by considering unceratinty and minimizing clinical risk. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
86. Damiano E. The importance of insulin pharmacokinetics in closed-loop control. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Oral Presentation)  
 
87. Del Favero S, Pillonetto G, De Nicolao G, Cobelli C. Individualization of artificial pancreas controller: A novel nonparametric strategy. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
88. Doyle III FJ. The design of control algorithhms for the artificial pancreas that yield robust performance and are safe for the patient. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Oral Presentation)  
 
89. El Youssef J, Syzbala C, Massoud RG, Engle J, Castle JR, DiMarchi R, Ward WK. Chemical stabilization of glucagon for use in dual-hormone closed-loop systems. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
90. Gerra S, Dalla Man C, Sparacino G, Renard E, Avogaro A, Maran A, Cobelli C. Glucose rate of appearance and plasma insulin concentration models for use in prediction algorithms. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
91. Grosman B, Dassau E, Zisser H, Jovanovic L, Doyle III FJ. Zone model predictive control based on an average subject model for the artificial pancreatic ß-cell. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Poster)  
 
92. Harvey RA, Dassau E, Zisser HC, Seborg DE, Jovanovic L, Doyle III FJ. Methods for reporting the performance of a hypoglycemia predictive algorithm. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Poster)  
 
93. Hughes CS, Patek SD, Dassau E, Breton M, Zisser HC, Doyle III FJ, Kovatchev B. Safety supervision system: In silico design and testing. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
94. Jimenez ND, Dassau E, Zisser HC, Jovanovic L, Doyle III FJ. The integration of five commercial devices makes the artificial pancreas system the most versatile platform available for the clinical evaluation of artificial pancreas control algorithms. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Poster)  
 
95. Kovatchev B. Engineering and clinical standards for closed-loop control of diabetes. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Oral Presentation)  
 
96. Kumareswaran K, Harris J, Allen J, Elleri D, Nodale M, Wilinska M, Amiel S, Heller S, Evans M, Hovorka R. Overnight closed-loop insulin delivery in adults with type 1 diabetes mellitus. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
97. Magni L, Toffanin C, Dalla Man C, Kovatchev B, Cobelli C, De Nicolao G. Range correction module with model-predictive control for type 1 diabetes. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
98. Morton D, Pourian N, Chen L, Bhargava K, Theorgarajan L, Zisser HC, Doyle III FJ, Dassau E. A wireless vital-sign monitoring system for enhanced insulin delivery. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Poster)  
 
99. Patek SD, Kovatchev B, Breton M, Cobelli C, Magni L, De Nicolao G, Dassau E, Zisser HC, Doyle III FJ. Engineering standards for closed-loop control of diabetes: Defining the artificial pancreas operating system. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Meeting Abstract)  
 
100. Renard E. Performance of closed-loop systems: What are the goals and how do we reach them?. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Oral Presentation)  
 
101. Ward WK. Novel glucagon formulations. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Oral Presentation)  
 
102. Weinzimer SA. Closed-loop control: What is holding us back and what can be done? Better insulin kinetics. Presented at the Diabetes Technology meeting, Bethesda, MD, 2010 (Published).
(Oral Presentation)  
 
103. Brosman B, Dassau E, Zisser H, Jovanovic L, Doyle FJ III. Simplified Zone Model Predictive Control for the Artificial Pancreatic Beta-Cell: An Average Population Model Approach. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
104. Dassau E. The Artificial Pancreas Architecture, Layers and Algorithms- A System Perspective. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
105. Dassau E, Jimenez ND, Zisser HC, Jovanovic L, Doyle FJ III. The Artificial Pancreas System, A Comprehensive System for the Clinical Evaluation of Control Algorithms. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
106. Elleri D, Allen JM, Nodale M, Wilinska ME, Mangat JS, Larsen AMF, Acerini CL, Dunger DB, Hovorka R. Automated Overnight Closed-Loop Glucose Control in Young Children with Type 1 Diabetes. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
107. Hovorka R. Overnight Closed-Loop Insulin Delivery. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
108. Hughes CS, Breton M, Patek SD, Kovatchev BP. Intercepting Insulin Bolus Requests- A Key Ingredient of Insulin Pump Safety Supervision. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
109. Kovatchev BP, Breton M, Hughes CS, Patek SD, Cobelli C, Renard E. Sequential Steps Towards Regulatory Approval and Clinical Acceptance of Closed-Loop Control: Safety First. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
110. Kumareswaran K, Harris J, Allen J, Elleri D, Nodale M, Wilinska M, Amiel S, Heller S, Evans M, Hovorka R. Closing the Loop Overnight in Adults with Type 1 Diabetes Following Standard Meal and Large Meal with Alcohol. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
111. Magni L, Toffanin C, Soru P, Dall Man C, Kovatchev B, De Nicolao G. Individualization of Model Predictive Control for the Artificial Pancreas from Standard CGM Traces. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
112. Mangat JS, Wilinska ME, Elleri D, Taub M, Hayter G, Harper W, White PA, Dunger DB, Hovorka R. Risk, Reason and Responsibility. Safe Design of a Home Use Artificial Pancreas System. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
113. Weinzimer SA, Sherr JL, Cengiz E, Palerm CC, Clark B, Kurtz N, Loutseiko M, Roy A, Carria L, Tamborlane WV. Closed Loop Insulin Delivery Reduces Nocturnal Hypoglycemia During Nights With or Without Antecedent Afternoon Exercise. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
114. Zisser H. Remote Monitoring of the Artificial Pancreas: Implications for the Future Clinical Management of Diabetes. Presented at the 4th International Conference on Advanced Technologies & Treatments for Diabetes, London, UK, 2011 (Published).
(Meeting Abstract)  
 
115. Breton MD, Patek SD, Demartini S, Farret A, Brown S, Hughes C, Place J, Dassau E, Zisser H, Doyle F III, Anderson S, Kovatchev B, Renard E. Modular advisory/automated control (AAC) reduces glucose excursions out of a safe range and hypoglycemia in adults and adolescents with type 1 diabetes. Oral presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Oral Presentation)  
 
116. Cengiz E, Martin M, Tamborlane WV, Weinzimer SA. Utilizing a novel infusion site warming device to quicken insulin action: the InsuPatch project. Poster presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Poster)  
 
117. Elleri D., Allen J.M., Kumareswaran K., Leelarathna L., Nodale M., Caldwell K., Murphy H., Wilinska M.E., Acerini C.L., Dunger D.B. and Hovorka R.. Day-and-Night Closed-Loop (CL) Glucose Control in Adolescents with Type 1 Diabetes (T1D). Oral presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Oral Presentation)  
 
118. Harvey RA, Dassau E, Zisser HC, Bevier W, Seborg D, Jovanovic L, Doyle FJ III. Analysis of a hypoglycemia prediction algorithm on an extensive library of ambulatory data. Poster presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Poster)  
 
119. Lee JJ, van Heusden K, Grosman B, Dassau E, Zisser H, Jovanovic L, Wollitzer AO, Doyle FJ III. Hybrid artificial pancreas using prandial inhaled insulin and zone MPC. Poster presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Poster)  
 
120. Mauseth R.S., Matheson D.P. and Kircher R.C.. Progress on a Method of Insulin Pump Control Using Fuzzy Logic. Printed Abstract, American Diabetes Association, San Diego, CA, 2011 (Published).
(Meeting Abstract)  
 
121. Nodale M., Haidar A., Wilinska M.E. and Hovorka R.. The Use of Continuous Glucose Monitoring (CGM) to Evaluate Performance of Closed-Loop Insulin Delivery Systems. Oral presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Oral Presentation)  
 
122. Renard E., Bruttomesso D., Magni L., Dalla Man C., Del Favero S., Toffanin C., Patek S., Hughes C., Place J., Farret A., Maran A., Vedovato M., Dassau E., Zisser H., Doyle F. III, Kovatchev B., De Nicalao G., Avogaro A., Breton M. and Cobelli C.. The Multi-Modular Model Predictive Control-to-Range (MPC2R) Allows Simultaneous Improvement in Safety and Efficiency of closed-Loop Insulin Delivery in Type 1 Diabetes (T1D). Oral presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Oral Presentation)  
 
123. Weinzimer S.A., Sherr J.L., Cengiz E., Palerm C.C., Clark B., Kurtz N., Loutseiko M., Roy A., Carria L. and Tamborlane W.V.. Glucose Control Using Closed Loop Insulin Delivery during Nights with or without Antecedent Afternoon Exercise. Oral presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Oral Presentation)  
 
124. Weinzimer SA, Sherr JL, Cengiz E, Kim G, Carria L, Tamborlane WV. Effect of adjuvant injected pramlintide on closed-loop automated insulin delivery. Poster presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Poster)  
 
125. Zhao C, Dassau E, Zisser H, Bevier W, Doyle FJ III, Jovanovic L, Seborg DE. Prediction of short-term glucose trends for type 1 diabetes using empirical models and frequency-band separation. Oral presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Oral Presentation)  
 
126. Zisser H, Bevier W, Dassau E, Markova K, Breton M, Kovatchev B. Novel methodology to determine the accuracy of insulin pumps - Key components of the artificial Pancreas System – Illustrated by an accuracy analysis of the OmniPod insulin pump. Poster presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Poster)  
 
127. Zisser H, Dassau E, Bevier W, Harvey R, Percival M, Grosman B, Seborg D, Jovanovic L, Doyle FJ III. Initial evaluation of a fully automated artificial pancreas. Oral presentation, American Diabetes Association, San Diego, CA, 2011 (Published).
(Oral Presentation)  
 
128. Rojas R, Garcia-Gabin W, Bequette B. Multivariate Statistical Analysis to Detect Insulin Infusion Set Failure. 2011 American Control Conference (Published).
(Meeting Abstract)  
 
129. Cameron F, Bequette B, Buckingham B, Wilson D, Lee H, Niemeyer G. Anticipatory Behavior in Blood Glucose Control: Using Meal Prior Probabilities to Prepare for Future Meal Disturbances. Preprints of the 18th IFAC World Congress (Published).
(Meeting Abstract)  
 
130. Rojas R, Garcia-Gabin W, Bequette B. Mean Glucose Slope – Principal Component Analysis Classification to Detect Insulin Infusion Set Failure. Preprints of the 18th IFAC World Congress (Published).
(Meeting Abstract)  
 
131. Mauseth R., Greenbaum C., Tridgell D., Sanda S., Kircher R., Matheson D., Bollyky J. Use of Fuzzy Logic (FL) Controller in a Closed Loop Artificial Pancreas. Presented at the Diabetes Tech Meeting Oct 2011 (Published).
(Poster)  
 
132. Cengiz E., Weinzimer S.A., Sherr J., Tichy E., Martin M., Carria L., Tamborlane W.. Acceleration of Insulin Action by Infusion Site Warming. 72nd Scientific Sessions of the American Diabetes Association, Philadelphia, PA Jun 8-12, 2012 (Published).
(Meeting Abstract)  
 
133. Sherr J.L., Palau Collazo M.M., Carria L.R., Steffen A.T., Zgorski M., Weyman K., Tichy E.M., Cengiz E., Tamborlane W.V., Weinzimer S.A.. Safety of Nighttime 2-hour Suspensions of Basal Insulin in Pump-treated Type 1 Diabetes (T1D) even in Absence of Low Glucose. 72nd Scientific Sessions of the American Diabetes Association, Philadelphia, PA Jun 8-12, 2012 (Published).
(Meeting Abstract)  
 
134. Cameron F., Patel P., Wilson D., Buckingham B., Bequette B.W.. Detecting Insulin Infusion Set Failure. Presented at the 5th International Conference on Advanced Technologies and Treatments of Diabetes, Barcelona, Spain, 2012 (Published).
(Oral Presentation)  
 
135. Harvey R.A., Dassau E., Zisser H.C., Seborg D.E., Jovanovic L., Doyle F.J. III,. The Health Monitoring System (HMS): A Multi-Component Safety System for the Artificial Pancreas. Presented at the 5th International Conference on Advanced Technologies and Treatments of Diabetes, Barcelona, Spain, 2012 (Published).
(Poster)  
 
136. Keith-Hynes P., Patek S.D., Breton M.D., Kovatchev B.P.,. Ambulatory Artificial Pancreas Platform (AAPP): Design Concepts and Prototype Demonstration. Presented at the 5th International Conference on Advanced Technologies and Treatments for Diabetes, Barcelona, Spain, 2012 (Published).
(Oral Presentation)  
 
137. Russell S., Nathan D.M., El-Khatib F.H., Damiano E.R.. A Comparative Analysis of Three Continuous Glucose Monitors: Not All Are Created Equal. Presented at the 5th International Conference on Advanced Technolgies and Treatments of Diabetes, Barcelona, Spain, 2012 (Published).
(Poster)  
 
138. Russell S.J., El-Khatib F.H., Magyar K.L., Nathan D.M., Damiano E.R.. Automated Management of Blood Glucose in Type 1 Diabetes with a Bi-hormonal Bionic Pancreas. Presented at the 5th International Conference on Advanced Technologies and Treatments for Diabetes, Barcelona, Spain, 2012 (Published).
(Oral Presentation)  
 
139. Toffanin C., Magni L., De Nicolao G., Zisser H., Kovatchev B., Dassau E., Doyle F.J. III, Dalla Man C., Cobelli C.,. Meal Regulation In Type 1 Diabetes: Model Predictive Artificial Pancreas Controller Enhanced By Insulin-On-Board Calculation. Presented at the 5th International Conference on Advanced Technologies and Treatments of Diabetes, Barcelona, Spain, 2012 (Published).
(Poster)  
 
140. Weinzimer S.A., Ruiz J.L., Sherr J.L., Cengiz E., Kim G., Carria L., Steffen A.T., Tamborlane W.V.. A Comparison of Strategoes for Controlling Post-Prandial Glucose Excursions During Closed-Loop Control. Presented at the 5th International Conference on Advanced Technologies and Treatments for Diabetes, Barcelona, Spain, 2012 (Published).
(Poster)  
 
141. Cameron F., Buckingham BA., Wilson DM., Bequette BW.. Extending Threshold-Based Detection of Infusion Set Failures. 2012 Diabetes Technology Meeting, Bethesda, MD (November 2012) (Published).
(Poster)  
 
142. Cameron F., Buckingham BA., Wilson DM., Niemeyer G., Bequette BW. Knowledge and Expectation of Meal Announcements in Meal Prior Probabilities for Glucose Control. 2012 Diabetes Technology Meeting, Bethesda, MD (November 2012) (Published).
(Poster)  
 
143. Castle JR., Nakamura K., Peyser TA., Ward WK.. Use of Redunant Dexcom New-Generation Sensors to Assess Sensor Accuracry and Performance. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
144. Del Favero S., Faccinetti A., Sparacino G., Cobelli C.,. Improving Overnight Safety of Type 1 Diabetes Subjects: Failure Detection Method of Glucose Sensor-Insulin Pumps System Based on an Average Mofel. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
145. Facchinetti A., Del Favero S., Castle JR., Ward KW., Sparacino G., Cobelli C.. Model of Sensor Error from Multiple Simultaneous Continuous Glucose Monitors in the Same Subject. J Diabetes Sci Technol January 2013 vol. 7 no. 1 281-A161 (Published).
(Meeting Abstract) |  View Publication  
 
146. Gondhalekar R., Dassau E., Lee J., Zisser H., Doyle FJ.. Model Predictive Control with Periodic Zones for All-Day Closed Loop Operation of an Artificial Pancreas. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
147. Hughes-Karvetski C., Guerlain S., Keith-Hynes P., McElwee M., Kovatchev B.. Formative Evaluation of the Artificial Pancreas System User Interface. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
148. Jiang B., Anderson SM., Breton MD.. Online Insulin Sensitivity Estimation in Type 1 Diabetes Mellitues: Enhancing Glycemic Prediction in the Artificial Pancreas Platform. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
149. Laxminarayan S., Reifman J., Steil GM.. Use of a Food and Drug Administration-Approved Type 1 Dibaetes Mellitus Simulator to Evaluate and Optimize a Proportional-Integral-Derivative Controller. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
150. Mayou P., Dassau E., Tompot R., Bhavaraju NC., Kamath A., Peyser T., Zisser H., Doyle FJ.. New Continuous Glucose Monitoring System for Artificial Pancreas Platform. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
151. Micheletto F., Dalla Man C., Kovatchev BP., Cobelli C.. The Updated University of Virginia/Padova Type 1 Diabetes Simulator. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
152. Place J., Robert A., Ben Brahim N., Breton M., Keith-Hynes P., Farret A., Kovatchev B., Renard E.. Remote Monitoring of Artificial PancreasL A Web-Based Application for Home Trials. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
153. Visentin R., Dalla Man C., Cobelli C.. Continuous-Glucose Monitoring-Informed Correction Bolus Advisor for Multiple Daily Injection Treatment of Type 1 Diabetes. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
154. Barnard K, Thabit H, Lubina-Solomon A, Stadler M, Walkinshaw E, IqbaL A, Nisbet C, Pernet A, Leelarathna L, Allen J, Tinati T, Heller S, Amiel S, Evans M, Hovorka R.. Overnight Closed-Loop Insulin Delivery: Psychosocial Impact for Adults with Type 1 Diabetes. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
155. Shah A, Block J, Floyd B, Evans-Behnke D, Hendry D, Buckingham B.. Effect of Shared Medical Appointments in Youth with Type 1 Diabetes in Poor Control. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
156. Umpierrez G, Digenio A, Goldenberg R, Hernandez-Triana E, Lin J, O'neal D, Park C, Renard E, Kovatchev B. Lixisenatide Added to Basal Insulin Reduces Glycemic Variability in T2DM Patients. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
157. Brown S, Bruttomesso D, Breton M, Favero S, Anderson S, Cobelli C, Kovatchev B.. Multinight Bedside" Artificial Pancreas for Patients with T1D Improves Glycemic Control". Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
158. Buckingham B, Cheng P,Beck R, Kollman C, Ruedy K, Weinzimer S, Slover R, Bremer A, Tamborlane W, Fuqua J.. Relationship of Glycemic Control and C-Peptide Levels 2 Years Following Diagnosis of T1D. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
159. Dasanayake I, Bevier W, Castorino K, Dassau E, Seborg D, Doyle III F.. Clinical Results of Smart Detection of Physical Activity in Adults with Type 1 Diabetes. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
160. Dimeglio L, Cheng P, Beck R, Kollman C, Ruedy K, Buckingham B, Weinzimer S, Slover R, Bremer A, Aye T.. Early Predictors of Stimulated C-Peptide in Persons with Type 1 Diabetes (T1D). Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
161. Elleri D, Allen J, Tauschmann M, El-Khairi R, Benitez-Aguirre P, Acerini C, Dunger D, Hovorka R.. Overnight Closed-Loop in Young Children with Type 1 Diabetes (T1D) Aged 3 to 6 Years: Comparison between Diluted Insulin vs. Standard Insulin Strength. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
162. Favero S, Place J, Kropff J, Messori M, Keith-Hynes P, Visentin R, Monaro M, Bruttomesso D, Galasso S, Boscari F, Toffanin C, Palma F, Lanzola G, Scarpellini S, Farret A, Kovatchev B, Magni L, Avogaro A, Devries J, Cobelli C, Renard E, On Behalf Of The Ap@Home Consortium. Multicenter Outpatient Wearable Artificial Pancreas (AP) Study: Improved Safety and Efficacy of Glycemic Control. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
163. Gondhalekar R, Dassau E, Brown S, Castorino K, Basu A, Kudva Y, Patek S, Zisser H, Doyle III F.. Automated Predictive Suspend and Resume of Insulin Delivery in a Randomized Multicenter Ambulatory Clinical Trial. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
164. Haller M, Cengiz E, Tamborlane W, Roy S, Thambundit A, Beck R, Kollman C, Ruedy K, Connor C, Buckingham B, Gregg B, Thomas I.. Frequency of Self-Monitoring of Blood Glucose (SMBG) and A1C Levels in Youth with Type 2 Diabetes (T2D): Data from the Pediatric Diabetes Consortium (PDC) T2D Registry Consortium (PDC) T2D Registry. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
165. Leelarathna L, Dellweg S, Mader J, Allen J, Benesch C, Doll W, Ellmerer M, Hartnell S, Heinemann L, Kojzar H, Michalewski L, Nodale M, Thabit H, Wilinska M, Pieber T, Arnolds S, Evans M, Hovorka R.. Factors Affecting the Performance of Day and Night Artificial Pancreas Under Real-World Conditions in Adults with Type 1 Diabetes. Presented at the American Diabetes Association meeting, San Francisco, CA, 2014 (Published).
(Poster)  
 
166. Brahim N, Place J, Renard E, Breton M. Designing a Decision Support System to Prevent Postexercise Hypoglycemia in Type 1 Diabetes. Presented at the Diabetes Technology Meeting, Bethesda, MD, 2014 (Published).
(Meeting Abstract)  
 
167. Buckingham B. Strategies to Increase Adherence to Technology. Presented at the Diabetes Technology Meeting, Bethesda, MD, 2014 (Published).
(Oral Presentation)  
 
168. Ketih-Hynes P. Wearable Devices and Network Platforms for Artificial Pancreas and Advanced Glucose Management. Presented at the Diabetes Technology Meeting, Bethesda, MD, 2014 (Published).
(Oral Presentation)  
 
169. Kovatchev B. Analyzing Performance Data Using the Surveillance Error Grid. Presented at the Diabetes Technology Meeting, Bethesda, MD, 2014 (Published).
(Oral Presentation)  
 
170. Hood K, Ambrosino J, Walders-Abramson N, Ly T, Maahs D, Weinzimer S, Buckingham B. Human Factors and Hybrid Closed-Loop: Experiences of Participants and Remote Monitors. Diabetes Technology & Therapeutics 17:A12-A12 · February 2015 (Published).
(Meeting Abstract)  
 
171. Chase HP, Maahs D, Wadwa P, Buckingham B, Wilson D, Ly T, Lum J, Calhoun P, Raghinaru D, Cameron F, Bequette BW, Hramiak I, Beck R. Hypoglycemia Reduction with Closed-Loop Systems by Age. Diabetes Technology & Therapeutics 17:A4-A4 · February 2015 (Published).
(Meeting Abstract)  
 
172. Ly T, Weinzimer S, Carria L, Maahs D, Messer L, Roy A, Grosman B, Cantwell M, Kurtz N, Buckingham B. Outpatient Day and Night Hybrid Closed-Loop Control with a Proportional-Integral-Derivative Based Algorithm in Adults with Type 1 Diabetes. Diabetes Technology & Therapeutics 2015 Feb 1 (Vol 17, ppA97-A98) (Published).
(Meeting Abstract) |  View Publication  
 
173. Barnard KD, Oliver N, Pinsker J, Astle A, Kerr D. Future Artificial Pancreas Technology for Type 1 Diabetes. What Do Users Want?. Presented at the Advanced Technologies & Treatments for Diabetes, Paris, France, February 2015 (Published).
(Meeting Abstract)  
 
174. Dassau E, Brown SA, Basu A, Pinsker JE, Kudva YC, Gondhalekar R, Patek S, Lv D, Schiavon M, Lee JB, Dalla man C, Kovatchev BP, Cobelli C, Zisser HC, Doyle III FJ. Multicenter Outpatient Randomized Crossover Trial of Zone-MPC Artificial Pancreas in Type 1 Diabetes: Effects of Initialization Strategies. Presented at the American Diabetes Association, Boston, MA, June 2015 (Published).
(Meeting Abstract)  
 
175. Desalvo DJ, Ly TT, Maahs DM, Messer LH, Pyle L, Wadwa P, Westfall E, Hanes S, Buckingham BA. Duration of Infusion Set Survival with Hyaluronidase Injected at Insulin Pump Infusion Site. Diabetes 2015 Jun 1 (Vol. 64, pp. A646-A646) (Published).
(Meeting Abstract)  
 
176. Kudva YV, Patek SK, Brown S, Basu A, Pinsker J, Kerr D, Lee JB, Gondhalekar R, Lv D, Schiavon M, Dalla man, C, Kovatchev BP, Cobelli C, Zisser HC, Doyle III FJ, Dassau E. Blinded Comparison of Expert Endocrinologists Adjustment of Insulin Pump Settings vs. Novel Initialization Algorithm-based Adjustment following a Data Gathering Period in a Multicenter Closed-Loop RCT. Presented at the American Diabetes Association, Boston, MA, June 2015 (Published).
(Meeting Abstract)  
 
177. Lee JB, Pinsker JE, Dassau E, Seborg DE, Bradley PK, Gondhalekar R, Bevier WC, Huyett L, Zisser HC, Doyle III FJ. Randomized Crossover Clinical Trial Comparing MPC and PID Control Algorithms for Artificial Pancreas. Presented at the American Diabetes Association, New Orleans, LA, June 2016 (Published).
(Meeting Abstract)  
 
178. Lee JB, Pinsker JE, Dassau E, Seborg DE, Castorino K, Gondhalekar R, Bevier WC, Bradley PK, Zisser HC, Doyle III FJ. Clinical Comparison of MPC and PID Artificial Pancreas Controllers: A Randomized Crossover Trial. Presented at the American Diabetes Association, Boston, MA, June 2015 (Published).
(Meeting Abstract)  
 
179. Triolo TM, Maahs DM, Cheng P, Pyle L, Buckingham BA, Slover R, Chase HP. Effects of Sensor Augmented Pump Use on HbA1c and C-Peptide in the First Year of Type 1 Diabetes. Tijdschr Diabetol (2015) 13: 62. doi:10.1007/s12467-015-0030-0 (Published).
(Meeting Abstract) |  View Publication  
 
180. David Maahs. Weak Points in Closed-loop Technoogy: Fault Detection and Mitigation. Presented at the Advanced Technologies & Treatment for Diabetes 9th International Conference, Milan, Italy, 2016 (Published).
(Meeting Abstract)  
 
181. Huyett L, Ly T, Reuschel-DiVirgilio S, Clay M, Bevier W, Gondhalekar R, Dassau E, Forlenza G, Doyle III F, Pinsker J, Maahs D, Buckingham B. Outpatient Closed-Loop Control with Unannounced Moderate Exercise in Adolescents using Zone Model Predictive Control. Presented at the 9th International Conference on Advanced Technologies & Treatments for Diabetes, Milan, Italy, 2016 (Published).
(Meeting Abstract)  
 
182. Patel N, Carria L, Tichy E, Weyman K, Steffen A, Zgorski M, Weinzimer S, Van Name M, Tamborlane W, Sherr J. Sipping for Safety: A Simple Snacking Strategy to Mitigate Hypoglycemia During Exercise while on Closed Loop Insulin Delivery. Presented at the 9th International Conference on Advanced Technologies & Treatments for Diabetes, Milan, Italy, 2016 (Published).
(Meeting Abstract)  
 
183. Rabasa-Lhoret R, Haidar A. Outpatient 60-Hour Day-and-Night Glucose Control with Dual-Hormone Artificial Pancreas, Single-Hormone Artificial Pancreas, or Sensor-Augmented Pump Therapy in Type 1 Diabetes: Rand Controlled Trail. Presented at the 9th International Conference on Advanced Technologies & Treatments for Diabetes, Milan, Italy, 2016 (Published).
(Meeting Abstract)  
 
184. Rabasa-Lhoret R, Haidar A. Stimulating Glycemic Control in Virtual Diabetes Patients. Presented at the 9th International Conference on Advanced Technologies & Treatments for Diabetes, Milan, Italy, 2016 (Published).
(Meeting Abstract)  
 
185. Rabasa-Lhoret R, Haidar A. The Efficacy of Single-and Dual-Hormone Artificial Pancreas Systems at Regulating Glucose Levels during Continuous and Interval Exercise in Type 1 Diabetes: Randomised Four-Way Trail. Presented at the 9th International Conference on Advanced Technologies & Treatments for Diabetes, Milan, Italy, 2016 (Published).
(Meeting Abstract)  
 
186. Farhy L, Patek S, Brown S, Ortiz E, Breton M, Kovatchev B. Glucose Excursions and Insulin Delivery Rates in the Field Predict In-Hospital Measured Glucagon Counterregulation in Adults with Type 1 Diabetes. Presented at the American Diabetes Association 76th Scientific Sessions, New Orleans, LA, 2016 (Published).
(Meeting Abstract)  
 
187. Stewart Z, Wilinska ME, Hartnell S, Simmons D, Temple R, Stanley K, Rayman G, Hovorka R, Murphy H. Closed-Loop Insulin Delivery in the Intrapartum and Early Postpartum Period in Women with Type 1 Diabetes in Pregnancy. Presented at the American Diabetes Association 76th Scientific Sessions, New Orleans, LA, 2016 (Published).
(Meeting Abstract)  
 
188. Cameron F, Baysal N, Buckingham B, Clinton P, Forlenza G, Howsmon D, Lam D, Levister C, Levy C, Ly T, Maahs D, Messer L, Patek S, Westfall E, Xie Y, Bequette BW. Hotel Trial of a Fully Closed-Loop Artificial Pancreas with Unannounced, Unscheduled Large Meals. Presented at the American Diabetes Association 76th Scientific Sessions, New Orleans, LA, 2016 (Published).
(Meeting Abstract)  
 
189. Chernavvsky D, Deboer M, Robic J, Kovatchev B, Breton M. Closed-Loop Control Reduces Hypoglycemia during Extended Winter-Sport Exercise in Youth with T1D: The AP Ski Camp. Presented at the American Diabetes Association 76th Scientific Sessions, New Orleans, LA, 2016. (Published).
(Meeting Abstract)  
 
190. Forlenza G, Cameron F, Baysal N, Buckingham B, Clinton P, Lam D, Levy C, Levister C, Ly T, Maahs D, Messer L, Patek S, Westfall E, Xie Y, Bequette W. Effect of Meal Detection Suppression on Postprandial Glycemic Excursion in Fully Closed-Loop Artificial Pancreas with Unannounced, Unscheduled Large Meals. Presented at the American Diabetes Association 76th Scientific Sessions, New Orleans, LA, 2016 (Published).
(Meeting Abstract)  
 
191. Garg S, Christiansen M, Brazg R, Bailey TS, Buckingham B, Anderson S, Weinzimer S, Bode B, Welsh J, Kaufman F. Glucose Concentrations and Rates of Change during Hypoglycemia Induction to Evaluate a Predictive Low Glucose Management (PLGM) System. Presented at the American Diabetes Association 76th Scientific Sessions, New Orleans, LA, 2016 (Published).
(Meeting Abstract)  
 
192. Hood K, Buckingham B, Ly T, Clinton P, Frank E, Hanes S, Selagamsetty R, El-Khatib F, Damiano E. Insulin-Only Bionic Pancreas: Preliminary Results. Presented at the American Diabetes Association 76th Scientific Sessions, New Orleans, LA, 2016 (Published).
(Meeting Abstract)  
 
193. Ruan Y, Thabit H, Leelarathna L, Hartnell S, Wilinska M, Dellweg S, Benesch C, Mader J, Holzer M, Kojzar H, Evans M, Arnolds S, Pieber T, Hovorka R. Insulin Pharmacodynamics and Outcomes during Home Use of Closed-Loop Insulin Delivery in Adults with Type 1 Diabetes. Presented at the American Diabetes Association 76th Scientific Sessions, New Orleans, LA, 2016 (Published).
(Meeting Abstract)  
 
194. Baysal N, Cameron F, Buckingham BA, Wilson DM, Bequette BW. Detecting Sensor and Insulin Infusion Set Anomalies in an Artificial Pancreas. Proceedings of the 2013 American Control Conference, Washington, DC. 2013; 2935-2939 (Published).
(Meeting Abstract)  
 
195. Baysal N, Cameron F, Buckingham BS, Wilson DM, Chase PH, Bequette BW.. Nocturnal CGM Signal Attenuation: An Outpatient Study. Presented at the Diabetes Technology meeting, Bethesda, MD, 2012 (Published).
(Meeting Abstract)  
 
196. Buckingham B.A., Cameron F., Lum J., Maahs D., Clinton P., Harris B., Realson J., Bequette W.B., Wilson D.M., Beck R., Chase P.H.. Outpatient In-Home Pilot Trial of Predictive Nocturnal Pump Shut-Off. 72nd Scientific Sessions of the American Diabetes Association, Philadelphia, PA Jun 8-12, 2012 (Published).
(Oral Presentation)  
 
197. Leelarathna, L., Nodale, M., Allen, J.A., Elleri, D., Kumareswaran, K., Haidar, A., Caldwell, K., Wilinska, M.E., Acerini, C.L., Evans, M.L., Murhpy, H.R., Dunger, D.B., Hovorka, R. Accuracy and Large Inaccuracy of Two Continuous Glucose Monitoring (CGM) Systems. Diabetes. June 2012; 61 (suppl 1): A1(3-OR) (Published).
(Oral Presentation)  
 
198. Nodale, M., Elleri, D., Allen, J.M., Kumareswaran, K., Harris, J., Haidar, A., Leelarathna, L., Caldwell, K., Murphy, H.R., WILINSKA, M.E., Acerini, C.L., Evans, M.L., Dunger, D.B., HOVORKA, R.. Factors Affecting Performance of Overnight Closed-Loop Insulin Delivery in Type 1 Diabetes (T1D). Diabetes. June 2012; 61 (suppl 1): A58 (219-P) (Published).
(Oral Presentation)  
 
199. Specht, B.J., Wadwa, R,P., Snell-Bergeon, J.K., Bishop, F.K., Maahs, D.M.. Estimated Insulin Sensitivity and Cardiovascular Disease Risk Factors in Adolescents With and Without Type 1 Diabetes. Diabetes. June 2012; 61 (suppl 1): A53 (197-OR) (Published).
(Oral Presentation)  
 
200. Weyman K., Zgorski M., Carria L.R., Sherr J.L., Cengiz E., Tamborlane W.V., Weinzimer S.A.. Changes in Basal and Bolus Insulin Requirements During Pramlintide Initiation and Dose Escalation in Young Adults with type 1 diabetes. Diabetes. June 2012; 61 (suppl 1): A615(2443-PO) (Published).
(Poster)  
 

Protocol PumpOff01 - Prevention of Nocturnal Hypoglycemia using predictive algorithms and pump shut-off.

1. Cameron F., Buckingham B.A., Wilson D.M., Chase H.P., Lum J., Bequette B.W.,. In-patient Studies of a Predictive Low Glucose Suspend System. Presented at the 5th International Conference on Advanced Technologies and Treatments for Diabetes, Barcelona, Spain, 2012 (Published).
(Oral Presentation)  
 

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